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Medical Science Monitor Basic Research

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MedSciTechnol

eISSN: 2329-0358

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Assessment of Health-Related Quality of Life of Patients after Kidney Transplantation in Comparison with Hemodialysis and Peritoneal Dialysis

Łukasz Czyżewski, Joanna Sańko-Resmer, Janusz Wyzgał, Andrzej Kurowski

(Department of Anaesthesiology, Institute of Cardiology, Warsaw, Poland)

Ann Transplant 2014; 19:576-585

DOI: 10.12659/AOT.891265


Background: The quality of life may determine the efficacy of renal replacement therapy (RRT). The purpose of the study was to compare the health-related quality of life (HRQOL) of end-stage renal disease (ESRD) patients depending on RRT method.
Material and Methods: The studies were conducted on 120 patients divided into 3 groups depending on RRT method: 30 peritoneal dialysis (PD) patients, 40 hemodialysis (HD) patients, and 47 post-kidney transplantation (KTx) patients. The following research tools were used: (1) Medical Outcomes Study 36 – the Short Form (SF-36 v.1); (2) Kidney Disease Quality of Life Short Form (KDQOL-SF™ v.1.3); and (3) disease history. The relevance level was p<0.05.
Results: The evaluation of PCS by HD and PD patients is poorer compared to patients in the 3rd and 12th month after KTx (34.7±7.4 vs. 37.51±10.63 vs. 45.01±9.43 vs. 45.55±8.62; p<0.05; respectively). PCS statistically significantly correlated with the following: SBP (r=–0.54; p<0.05), DBP (r=–0.58; p<0.05), and creatinine concentration (r=0.46; p<0.05) in the 12th month after KTx.
Conclusions: HRQOL of ESRD patients differed depending on the RRT method: top values were shown by post-KTx patients, lower by PD patients, and the bottom ones by HD patients. Along with patient age, increased BP, and BMI, a drop in value of HRQOL in post-Tx or PD patients was observed. When choosing RTT method, patients may use the results of the evaluation of quality of life. A preferred lifestyle, and predominantly the work status and quality of social interaction, should decide the choice of treatment.

Keywords: Hypertension, Kidney Transplantation, Peritoneal Dialysis, Quality of Life, Renal Dialysis, Renal Replacement Therapy

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
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