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Medical Science Monitor Basic Research

AmJCaseRep
MedSciTechnol

eISSN: 2329-0358

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Intention of Donors to Re-Donate Livers after Living Donor Liver Transplantation in a Liver Transplant Center in Asia

Yuan-Min Chang, Kuo-Piao Chung, Teng-Wei Chen, Chung-Bao Hsieh

(Division of General Surgery, Division of Organ Transplants, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan)

Ann Transplant 2014; 19:421-426

DOI: 10.12659/AOT.890821


Background: The aim of this study was to examine donor complications, satisfaction with the liver donation process, and factors associated with re-donation.
Material and Methods: To address these issues, we conducted a cross-sectional study to assess donor complications and used questionnaires (including the Likert scale for donation satisfaction and simple yes/no responses for willingness to re-donate) in 110 adults who underwent living donor liver transplantation (LDLT) at Tri-Service General Hospital. The following clinical characteristics were determined: donation volume; first-degree relative; education; duration of hospital stay; occupation (donor-associated); MELD score; Child classification; complications; outcome (recipient-associated); and graft/recipient weight ratio (donor-recipient-associated). Descriptive statistics and mean values were compared using t-tests and p values <0.05 were considered significant.
Results: Twelve donors among 110 participants experienced complications above Clavien grade II. No surgical mortalities were observed. There were no differences in age, gender, left/right liver graft, donation volume, length of hospital stay, or satisfaction in donor complications. Ninety-four donors had satisfaction (score=4 and 5) about the donation process and no dissatisfaction was reported (score=1). Based on multivariate analysis, the intention to re-donate among liver donors was related to first-degree relatives, donor satisfaction, and recipient complications (P<0.05).
Conclusions: Factors associated with a willingness to re-donate included first-degree relatives of the recipient, donor satisfaction with the donation process, and recipient complications. This study not only showed the safety of liver donation, but also had a positive effect on the intention to re-donate to enhance motivation for liver donation and increase the recruitment of living liver donors.

Keywords: Liver Transplantation, Patient Satisfaction, Tissue and Organ Procurement

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
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