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Medical Science Monitor Basic Research


eISSN: 2329-0358

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Intention of Donors to Re-Donate Livers after Living Donor Liver Transplantation in a Liver Transplant Center in Asia

Yuan-Min Chang, Kuo-Piao Chung, Teng-Wei Chen, Chung-Bao Hsieh

(Division of General Surgery, Division of Organ Transplants, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan)

Ann Transplant 2014; 19:421-426

DOI: 10.12659/AOT.890821

Background: The aim of this study was to examine donor complications, satisfaction with the liver donation process, and factors associated with re-donation.
Material and Methods: To address these issues, we conducted a cross-sectional study to assess donor complications and used questionnaires (including the Likert scale for donation satisfaction and simple yes/no responses for willingness to re-donate) in 110 adults who underwent living donor liver transplantation (LDLT) at Tri-Service General Hospital. The following clinical characteristics were determined: donation volume; first-degree relative; education; duration of hospital stay; occupation (donor-associated); MELD score; Child classification; complications; outcome (recipient-associated); and graft/recipient weight ratio (donor-recipient-associated). Descriptive statistics and mean values were compared using t-tests and p values <0.05 were considered significant.
Results: Twelve donors among 110 participants experienced complications above Clavien grade II. No surgical mortalities were observed. There were no differences in age, gender, left/right liver graft, donation volume, length of hospital stay, or satisfaction in donor complications. Ninety-four donors had satisfaction (score=4 and 5) about the donation process and no dissatisfaction was reported (score=1). Based on multivariate analysis, the intention to re-donate among liver donors was related to first-degree relatives, donor satisfaction, and recipient complications (P<0.05).
Conclusions: Factors associated with a willingness to re-donate included first-degree relatives of the recipient, donor satisfaction with the donation process, and recipient complications. This study not only showed the safety of liver donation, but also had a positive effect on the intention to re-donate to enhance motivation for liver donation and increase the recruitment of living liver donors.

Keywords: Liver Transplantation, Patient Satisfaction, Tissue and Organ Procurement

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