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Medical Science Monitor Basic Research

AmJCaseRep
MedSciTechnol

eISSN: 2329-0358

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Pharmacological Surrogates of Allograft Outcome

Kamran Mahalati, Barry D Kahan

Ann Transplant 2000; 5(2): 14-23

ID: 497520


While new immunosuppressive agents have primarily reduced the incidence of acute rejection episodes, thereby reducing early morbidity and costs, chronic processes remain a major cause of graft loss [1,2]. Among the multiple factors that determine the interactions between host and graft, optimization of the immunosuppressive regimen is potentially the most modifiable and thus important factor in preventing the progression of rejection processes that determine graft
survival...

Keywords: Pharmacokinetics, cyclosporin, pharmacodynamics, Tacrolimus, Sirolimus

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
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