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Medical Science Monitor Basic Research


eISSN: 2329-0358

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Surrogate Biomarkers of Long-term Outcome after Kidney Transplantation

Leendert C Paul

Ann Transplant 2000; 5(2): 5-6

ID: 497518

A recent analysis of the USRDS material has shown that the median cadaveric renal transplant survival has improved from 64.5 months in 1986-1987 to 101.8 months in 1992-1993[1], an improvement of almost 60%. The reason for this improved outcome is multifactorial and reflects very likely improved patient survival, increasing experience, and more potent immunosuppression. Chronic rejection remains the main reason for graft failure with censoring for death with a functioning transplant.

Keywords: chronic rejection, Kidney Transplantation, long term outcome, biomarkers

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