Scimago Lab
powered by Scopus
call: +1.631.629.4327
Mon-Fri 10 am - 2 pm EST


Medical Science Monitor Basic Research


eISSN: 2329-0358

Get your full text copy in PDF

The Effect of Endocrine Disturbances on Hemodynamic Stability of Brain Dead Organ Donors. I. Thyroid Function

M Szostek, Z Gaciong, S Cajzner, B Lagiewska, M Pacholczyk, J Walaszewski, W Rowinski

Ann Transplant 1996; 1(2): 27-30

ID: 496655

The brain stem death is associated with hemodynamic, endocrine and metabolic disturbances which lead to multiorgan failure and, eventually, to circulatory arrest [1,8,17]. Early graft dysfunction caused by acute tubular necrosis is usually due to ischemia of donor kidneys in the period before harvesting. Hypothyroidism reduces intracellular energy stores and increases anaerobic metabolism and some authors advocated administration of triiodothyronine (D) in order to improve donor's cardiovascular status [11]. In this study we evaluated the thyroid function in 20 brain-dead donors and tried to correlate the biochemical changes in thyroid hormones with hemodynamic stability of these patients and renal allograft function after transplantation.

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
I agree