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Medical Science Monitor Basic Research


eISSN: 2329-0358

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Living emotionally related renal transplantation (LERT)--single center experience in the Balkans.

K Zafirovska, J Masin, K Cakalaroski, P Kolevski, Z Popov, N Ivanovski

Ann Transplant 2004; 9(2): 48-49

ID: 142781

BACKGROUND: As elsewhere, the growing organ shortage is a main problemfor organ transplantation. To solve the problem, we started accepting genetically unrelated, but emotionallyrelated living donors. METHODS: In the period of 1998-2002, 14 LERT are performed in the University ClinicalCentre in Skopje, Republic of Macedonia. As suitable donors are used predominantly spouses, but alsomother and brother in law. The immunosuppression included a quadruple protocol with Interleukin-2R antagonists,late cyclosporin A, MMF and steroids. The two-year graft and patients survival of LERT was compared with22 living genetically related donor transplantation (LRT) performed in the same time. RESULTS: The twoyears graft survival was 100% in LERT and 92% in LRT. There are not any significant difference amongthe medical and surgical complications between the two groups of pts. The actual serum creatinin was101+22 in LERT compared with 142+34 in LRT. CONCLUSION: The authors recommend the LERT as a valid alternativeespecially in the countries where the regular cadaver transplantation is not yet established.

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