07 June 2022: Original Paper
Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of Differences Between Alcohol-Related and Non-Alcohol-Related Cirrhosis Candidates
Jan-Paul Gundlach 1EF** , Felix Braun 1AD* , Finn Mötter 1B , Alexander Bernsmeier 1CDE , Pablo Barrio 2E , Nicola Ehmke 1B , Rainer Günther 3B , Holger Hinrichsen 4A , Thomas Becker 1AD , Wolfgang Weinmann 5B , Alexandra Schröck 6C , Michel Yegles 7C , Friedrich Martin Wurst 8ACDEDOI: 10.12659/AOT.936293
Ann Transplant 2022; 27:e936293
Table 1 Patient characteristics, biomarker values, and follow-up data, showing the number of patients (n), range, mean value and standard deviation (SD) for demographic parameters, expression of liver values, and AUDIT results, as well as number of positive test results, range, mean value and SD for uEtG, hEtG, PEth (16: 0/18: 2), and realized liver transplantations (LT) within the follow-up period for the total group as well as for the biomarker groups.
| Agen=66 | ASAT (U/L) n=66 | ALAT (U/L) n=66 | μGT (U/L) n=66 | MCV (fl) n=66 | AUDITn=66 | uEtG (mg/L) n=65 | hEtG (pg/mg) n=65 | PEth (ng/mL) n=66 | |
|---|---|---|---|---|---|---|---|---|---|
| Positive results (%) | 5 (7.7) | 9 (13.8) | 34 (51.5) | ||||||
| Min | 21.0 | 17.4 | 6.8 | 14.0 | 29.0 | 0.0 | 0.20 | 7.3 | 20.6 |
| Max | 74.0 | 229.0 | 313.9 | 1034.0 | 98.7 | 16.0 | 3.6 | 78.0 | 606.0 |
| Mean | 53.3 | 57.1 | 43.2 | 132.1 | 84.8 | 2.1 | 1.5 | 40.4 | 89.5 |
| SD | 12.02 | 42.70 | 45.96 | 167.76 | 11.42 | 3.21 | 1.64 | 26.05 | 112.25 |
| LT performed (%) | 23 (34.9) | 1 (20.0) | 4 (44.4) | 9 (26.5) | |||||
| Deaths after LT (%) | 6 (9.1) | 0 (0.0) | 2 (50.0) | 1 (11.1) | |||||
| Deaths without LT (%) | 9 (20.9) | 0 (0.0) | 1 (20.0) | 5 (14.7) | |||||