22 February 2022: Original Paper
Patient-Related Preoperative Clinical Factors Influencing 1-Year Survival After Orthotopic Heart Transplantation – A Single Center Polish Experience
Agnieszka Kuczaj 12ABCDEF* , Szymon Pawlak 13A , Piotr Przybyłowski 12D , Szymon Warwas 45B , Joanna E. Śliwka 3E , Michał Zakliczyński 6D , Tomasz Hrapkowicz 12DEDOI: 10.12659/AOT.934185
Ann Transplant 2022; 27:e934185
Table 1 Clinical baseline characteristics of patients and factors associated with 1-year survival (univariable analysis).
| Clinical factor | Total (n=258) | Hazard ratio, (range), confidence interval: 95% | P |
|---|---|---|---|
| Sex (female) | 59 (22.9%) | 1.692, (0.862–3.323) | 0.13 |
| Age, years | 53.5 (±11.8) | 1.023, (1.000–1.046) | 0.05 |
| Body weight, kg | 73.72 (±14.5) | 1.028, (1.010–1.047) | 0.06 |
| Height, m | 1.72 (±0.09) | 4.551, (0.203–102.294) | 0.34 |
| BMI, kg/m | 24.5 (±3.9) | 1.106, (1.036–1.181) | 0.28 |
| Urgent list | 113 (53.6%) | 1.509, (0.95–2.397) | 0.08 |
| Diabetes | 81 (31.8%) | 1.403, (0.827–2.382) | 0.21 |
| Impaired glucose tolerance | 18 (7%) | 1.061, (0.377–2.990) | 0.91 |
| COPD | 17 (6.7%) | 0.196, (0.027–1.415) | 0.11 |
| Stroke/TIA | 43 (18.6%) | 1.013, (0.551–1.862) | 0.97 |
| Ischemic etiology | 99 (43%) | 2.051, (1.227–3.429) | 0.01 |
| Reversible pulmonary hypertension | 35 (15.3%) | 0.907, (0.407–2.017) | 0.81 |
| Mechanical circulatory support | 56 (21.96%) | 1.474, (0.842–2.580) | 0.17 |
| LVAD | 40 (15.7%) | 1.953, (1.090–3.499) | 0.02 |
| ECMO | 4 (1.6%) | 3.502, (0.855–14.34) | 0.08 |
| IABP | 22 (8.7%) | 0.164, (0.023–1.186) | 0.07 |
| Serum creatinine, mmol/L | 116.97 (±46.4) | 1.004, (1.000–1.008) | 0.09 |
| GFR | 82 (35.6%) | 0.989, (0.977–1.000) | 0.06 |
| PVR (Wood units) | 2.04 (±1.17) | 1.013, (0.803–1.277) | 0.92 |
| Aspartate transaminase, U/L | 64.72 (±294) | 0.998, (0.994–1.003) | 0.44 |
| Alanine aminotransferase, U/L | 62.8 (±240.5) | 0.998, (0.993–1.002) | 0.32 |
| Bilirubin, mmol/L | 17.8 (±18.4) | 1.005, (0.993–1.017) | 0.41 |
| Albumin level, g/L | 42 (±6.6) | 0.978, (0.943–1.015) | 0.25 |
| Protein level, g/L | 70.2 (±9.98) | 0.982, (0.960–1.006) | 0.13 |
| A value | |||