01 December 2021>: Original Paper
Solid-Phase C1q/C3d Fixing Readouts Correlate with High Median Fluorescence Intensity (MFI) De Novo Donor-Specific HLA Antibodies and C4d Antibody-Mediated Rejection in Kidney Transplant Recipients
Vasishta S. Tatapudi 1*BDEF# , Dessislava Kopchaliiska 2ABC* , Gilberto J. da Gente 2C , Owen F. Buenaventura 2BC , Manpreet Singh 1BC$ , Zoltan Laszik 3BC , Deborah B. Adey 1CDE , Raja Rajalingam 2ADEF*DOI: 10.12659/AOT.934175
Ann Transplant 2021; 26:e934175
Table 1 Demographic and clinical characteristics of kidney transplant recipients developing de novo donor-specific HLA antibodies (n=120).
% (n)/Mean±SD | |
---|---|
Age at transplantation (y) | 47±18 years |
Gender; Female | 40% (48) |
Ethnicity/Race | |
Caucasian | 40% (48) |
African-American | 29% (35) |
Asian | 26% (31) |
Hispanic/Latino | 5% (6) |
Blood type | |
A | 42% (50) |
B | 10% (12) |
O | 43% (52) |
AB | 5% (6) |
Pre-tx CPRA | |
0–9% | 28% (34) |
10–79% | 51% (61) |
80+% | 21% (25) |
Primary transplantation | 86% (103) |
Re-transplantation | 14% (17) |
Age (y) | 41±15 |
Gender; Female | 42% (50) |
Living donor | 30% (36) |
Deceased donor | 70% (84) |
Kidney only | 91% (109) |
Kidney and Pancreas | 9% (11) |
Number of HLA-A/B/Cw/DR/DQ MM | 7.7±2.3 |