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01 October 2021: Original Paper

Outcomes After Living Donor Liver Transplantation in Pediatric Patients with Inherited Metabolic Diseases

Yukihiro Sanada ABCDEF* , Yasunaru Sakuma DF , Yasuharu Onishi B , Noriki Okada B , Naoya Yamada B , Yuta Hirata B , Go Miyahara B , Takumi Katano B , Toshio Horiuchi B , Takahiko Omameuda B , Alan Kawarai Lefor DF , Naohiro Sata DF

DOI: 10.12659/AOT.932994

Ann Transplant 2021; 26:e932994

Table 5 Post-transplant survival rates of patients with IMDs.

InstitutionsNumber of patientsSurvivalComplications or others
McKiernan PJ (2019) []SRTR1 2354 (17%)5-year graft: 94.5%
Kim JS (2015) []Asan Medical Center2 54 (1.6%)1-year graft: 88.8%5-year graft: 85.5%10-year graft: 85.5%
Mazariegos G (2014) []Children’s Hospital of Pittsburgh3 2851-year graft: 79.3%5-year graft: 73.1%10-year graft: 67.4%20-year graft: 56.9%
Kasahara M (2014) []Japan registry4 194 (8.7%)1-year graft: 91.2%5-year graft: 87.9%10-year graft: 86.1%15-year graft: 74.4%
Arnon R (2010) []SPLIT registry5 446 (14.9%)1-year graft: 90.8%5-year graft: 83.8%
Stevenson T (2010) []Stanford University6 54recipient: 100%(Observation period: 5.4±4.4 year)
Sze YK (2009) []King’s college Hospital7 96 (16.7%)1-year graft: 83%5-year graft: 77%10-year graft: 62%
Morioka D (2005) []Kyoto University8 46 (8.0%)1-year recipient: 86.8%5-year recipient: 81.2%10-year recipient: 81.2%
Kayler LK (2003) []UNOS9 551 (20.2%)1-year recipient: 94%5-year recipient: 92%
Our studyJichi Meidcal University44 (14.0%)1-year graft: 90.9%5-year graft: 90.9%10-year graft: 87.1%
IMDs – inherited metabolic diseases; SRTR – the Scientific Registry of Transplant Recipients; LT – liver transplantation; LDLT – living donor liver transplantation; DDLT – deceased donor liver transplantation; UCD – urea cycle disorders; MSUD – maple syrup urine disease; UNOS; the United Network for Organ Sharing.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358