Wilson Disease in Children; Chelation Therapy or Liver Transplantation? A 10-Year Experience from Pakistan

05 October 2021: Original Paper

Sahira Aaraj ^1CDE* , Sabeen Abid Khan ^1DF , Naurin Ali ^1BF , Munir I. Iqbal Malik ^2ADF , Faisal Saud Dar ^3AF

DOI: 10.12659/AOT.932606

Ann Transplant 2021; 26:e932606

Table 5 Outcome of liver transplantation in patients with Wilson disease.

Year of publication and country	Period of liver transplant	Number	Population	Indication	Follow up	Type of liver transplant	Patient surviuval	Re transplant
Guillaud et al 2014, France []²⁸	1985–2009	121	75 adults46 children	59 (FHF)50 (CLD)7 (Neurologic WD)	6 years	4 LDLT	87% (5, 10 years)	4 children13 adults
Markiewicz-Kijewska et al 2008, Poland []²⁹	1999–2007	11	13 children	13 (FHF)	7.43 years	2 LDLT	81.8% at 7 years
Sandra et al 2014, [] Austria³⁰	1961–2013	30		11 (FHF)1 (CLD)18 (Neurological WD)	20 years		83.3%	2
Cohort from Pakistan	2010–2020	11	11 children	7 (FHF)4 (CLD)	7 years	All LDLT	100% at 7 years	None