Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

09 November 2021: Original Paper

Type 1 Diabetic Patients After Simultaneous Pancreas and Kidney Transplantation Have Less Intense Periodontal Inflammation Compared to Kidney Recipients Treated with Insulin

Mikołaj Musiał 1ABCDEF* , Rafał Wiench 2ADEF , Aureliusz Kolonko 3BD , Piotr Choręza 4CD , Elżbieta Świętochowska 5BC , Damian Niedzielski 6BF , Agnieszka Machorowska-Pieniążek 1DG , Dariusz Skaba 2DE , Andrzej Więcek 3DE , Aleksander J. Owczarek 7CD , Iwona Niedzielska 6AD , Robert Król 8DE , Jacek Ziaja 8ADEF

DOI: 10.12659/AOT.932426

Ann Transplant 2021; 26:e932426

Table 2 Comparison of selected parameters concerning periodontal lesions and concentration of analyzed inflammatory markers in gingival crevicular fluid between the groups of type 1 diabetic patients after simultaneous pancreas-kidney transplantation (SPK) or kidney transplantation (KTx) and control group (numbers and rates or mean±SD or median and IQR).

SPKN=20KTxN=16ControlN=15ppSPK vs KTxpKTx vs controlpSPK vs control
Maximal pocket depth [mm]2.68 (2.26–3.69)2.55 (2.14–3.39)1.57 (1.00–1.96)1.00
Maximal clinical attachment loss [mm]2.96 (2.30–3.84)2.70 (1.92–4.31)0.55 (0.15–0.81)0.85
Modified Sulcus Bleeding Index [%]23.5 (14.0–41.5)66.5 (29.5–89.5)17.0 (13.0–22.0)0.090.67
Tooth mobility [periotest value]4.72 (2.50–9.02)5.15 (2.72–9.21)1.78 (1.36–2.20)0.99
Gingival crevicular fluid volume [U]0.37±0.110.53±0.260.29±0.120.38
IL-1 [pg/mL]26.03±7.5639.44±11.1618.82±9.410.10
MMP-8 [ng/mL]2.48±0.803.85±1.162.00±0.890.36
Resistin [ng/mL]22.81±3.9231.22±6.4912.81±3.82
TNFα [pg/mL]1.88 (1.65–2.09)2.57 (2.08–3.22)1.68 (1.49–1.94)0.54
YKL40 [pg/mL]524.1±117.4728.1±111.5341.4±66.2
IL-1β – interleukin-1β; MMP-8 – matrix metalloproteinase-8; TNF-α – tumor necrosis factor-α.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358