09 November 2021>: Original Paper
Type 1 Diabetic Patients After Simultaneous Pancreas and Kidney Transplantation Have Less Intense Periodontal Inflammation Compared to Kidney Recipients Treated with Insulin
Mikołaj Musiał 1ABCDEF* , Rafał Wiench 2ADEF , Aureliusz Kolonko 3BD , Piotr Choręza 4CD , Elżbieta Świętochowska 5BC , Damian Niedzielski 6BF , Agnieszka Machorowska-Pieniążek 1DG , Dariusz Skaba 2DE , Andrzej Więcek 3DE , Aleksander J. Owczarek 7CD , Iwona Niedzielska 6AD , Robert Król 8DE , Jacek Ziaja 8ADEFDOI: 10.12659/AOT.932426
Ann Transplant 2021; 26:e932426
Table 1 Clinical characteristics, biochemical parameters, and immunosuppressive treatment in type 1 diabetic patients after simultaneous pancreas and kidney transplantation (SPK) or kidney transplantation (KTx), and control group (numbers and rates or mean±SD or median and IQR).
SPKN=20 | KTxN=16 | ControlN=15 | P | |
---|---|---|---|---|
Sex (Male) [N (%)] | 8 (40.0%) | 9 (56.3%) | 5 (33.3%) | 0.41 |
Age at the time of Tx [years] | 38±6 | 41±12 | 34±11 | 0.21 |
Age at the time of study [years] | 45±6 | 49±12 | 45±13 | 0.46 |
Diabetes duration – prior to Tx [years] | 27.1±5.4 | 22.5±6.7 | --- | |
Diabetes duration – total [years] | 26.5 (24.0–31.0) | 32.0 (29.0–35.0) | --- | |
Dialysis vintage [months] | 24.0 (14.5–32.0) | 18.0 (12.5–25.0) | 18.0 (15.0–30.0) | 0.58 |
Follow-up after Tx [months] | 84.0 (42.0–102.0)* | 96.0 (48.0–156.0) | 132.0 (96.0–156.0) | |
BMI [kg/m] | 23.13±3.58 | 24.72±5.09 | 25.56±3.17 | 0.19 |
Overweight patients [N (%)] (BMI >25 kg/m) | 6 (30.0%) | 6 (37.5%) | 9 (60.0%) | 0.19 |
Serum creatinine [μmol/L] | 89.1 (72.3–106.8) | 106.5 (83.4–180.8) | 128.1 (85.2–155.4) | |
Patients with eGFR >60 mL/min/1.73 m [N (%)] | 14 (70.0%) | 6 (42.9%) | 5 (35.7%) | 0.10 |
Glycated hemoglobin [%] | 5.30 (5.12–5.67) | 7.13 (6.31–7.72) | --- | |
Tacrolimus [N (%)] | 19 (95.0%)** | 12 (75.0%) | 8 (57.1%) | |
Mofetil mycophenolate [N (%)] | 20 (100.0%) | 16 (100.00%) | 11 (78.6%) | --- |
Steroids [N (%)] | 7 (35.0%) | 7 (43.8%) | 4 (28.6%) | 0.68 |
Tx – transplantation; BMI – body mass index; eGFR – estimated glomerular filtration rate. * SPK vs control ** SPK vs control |