28 May 2021>: Original Paper
Risk Factors Affecting Outcomes in Pediatric Liver Transplantation: A Real-World Single-Center Experience
Suk Kyun Hong ABCDEF , Nam-Joon Yi ABCDEF* , Kwangpyo Hong BE , Eui Soo Han BE , Jeong-Moo Lee BE , YoungRok Choi BE , Kwang-Woong Lee BE , Kyung-Suk Suh BEDOI: 10.12659/AOT.929145
Ann Transplant 2021; 26:e929145
Table 5 Univariate and multivariate analysis of factors associated with postoperative hepatic artery complication.
Variables | n | Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|---|
Hepatic artery complication (%) | P value | HR | 95% CI | P value | ||
Sex | 0.839 | |||||
Male | 116 | 6 (5.2) | ||||
Female | 139 | 8 (5.8) | ||||
Age, year | 0.547 | |||||
72 | 5 (6.9) | |||||
≥1 | 183 | 9 (4.9) | ||||
Body weight, kg | 0.174 | |||||
14 | 2 (14.3) | |||||
≥6 | 241 | 12 (5.0) | ||||
Period of LT | 0.317 | |||||
Early (1988–2007) | 117 | 5 (4.0) | ||||
Middle (2008–2011) | 60 | 4 (7.4) | ||||
Recent (2012–2018) | 78 | 5 (6.5) | ||||
Type of LT | 0.475 | |||||
LDLT | 164 | 11 (6.7) | ||||
Whole-liver DDLT | 53 | 1 (1.9) | ||||
Split DDLT | 38 | 2 (5.3) | ||||
Underlying disease | ||||||
BA vs others | 0.036 | |||||
BA | 142 | 4 (2.8) | 0.78 | 0.14–4.40 | 0.781 | |
Others | 113 | 10 (8.8) | Reference | |||
Fulminant vs others | 0.013 | |||||
Fulminant | 29 | 5 (17.2) | 1.74 | 0.37–8.07 | 0.482 | |
Others | 226 | 9 (4.0) | Reference | |||
Chronic liver disease vs others | 0.004 | |||||
Chronic liver disease | 198 | 6 (3.0) | Reference | |||
Others | 57 | 8 (14.0) | 5.22 | 1.73–15.76 | 0.003 | |
PELD score | 0.169 | |||||
214 | 11 (5.1) | |||||
≥30 | 25 | 3 (12.0) | ||||
Child-Pugh score | 0.307 | |||||
A | 45 | 4 (8.9) | ||||
B, C | 194 | 10 (5.2) | ||||
Donor sex | 0.839 | |||||
Male | 139 | 8 (5.8) | ||||
Female | 116 | 6 (5.2) | ||||
Donor age, years | 1.000 | |||||
44 | 2 (4.5) | |||||
≥18 | 211 | 2 (5.7) | ||||
Relationship to recipient | 0.768 | |||||
Mother | 79 | 5 (6.3) | ||||
Other than mother | 176 | 9 (5.1) | ||||
HR – hazard ratio; CI – confidence interval; LT – liver transplantation; LDLT – living donor liver transplantation; DDLT – deceased donor liver transplantation; BA – biliary atresia; PELD – pediatric end-stage liver disease. |