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28 May 2021: Original Paper

Risk Factors Affecting Outcomes in Pediatric Liver Transplantation: A Real-World Single-Center Experience

Suk Kyun Hong ABCDEF , Nam-Joon Yi ABCDEF* , Kwangpyo Hong BE , Eui Soo Han BE , Jeong-Moo Lee BE , YoungRok Choi BE , Kwang-Woong Lee BE , Kyung-Suk Suh BE

DOI: 10.12659/AOT.929145

Ann Transplant 2021; 26:e929145

Table 5 Univariate and multivariate analysis of factors associated with postoperative hepatic artery complication.

VariablesnUnivariate analysisMultivariate analysis
Hepatic artery complication (%)P valueHR95% CIP value
Sex0.839
 Male1166 (5.2)
 Female1398 (5.8)
Age, year0.547
725 (6.9)
 ≥11839 (4.9)
Body weight, kg0.174
142 (14.3)
 ≥624112 (5.0)
Period of LT0.317
 Early (1988–2007)1175 (4.0)
 Middle (2008–2011)604 (7.4)
 Recent (2012–2018)785 (6.5)
Type of LT0.475
 LDLT16411 (6.7)
 Whole-liver DDLT531 (1.9)
 Split DDLT382 (5.3)
Underlying disease
 BA vs others0.036
  BA1424 (2.8)0.780.14–4.400.781
  Others11310 (8.8)Reference
 Fulminant vs others0.013
  Fulminant295 (17.2)1.740.37–8.070.482
  Others2269 (4.0)Reference
 Chronic liver disease vs others0.004
  Chronic liver disease1986 (3.0)Reference
  Others578 (14.0)5.221.73–15.760.003
PELD score0.169
21411 (5.1)
 ≥30253 (12.0)
Child-Pugh score0.307
 A454 (8.9)
 B, C19410 (5.2)
Donor sex0.839
 Male1398 (5.8)
 Female1166 (5.2)
Donor age, years1.000
442 (4.5)
 ≥182112 (5.7)
Relationship to recipient0.768
 Mother795 (6.3)
 Other than mother1769 (5.1)
HR – hazard ratio; CI – confidence interval; LT – liver transplantation; LDLT – living donor liver transplantation; DDLT – deceased donor liver transplantation; BA – biliary atresia; PELD – pediatric end-stage liver disease.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358