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15 December 2020: Original Paper

The Impact of Hypothermic Pulsatile Machine Perfusion Versus Static Cold Storage: A Donor-Matched Paired Analysis in a Scenario of High Incidence of Delayed Kidney Graft Function

Tainá Veras de Sandes-Freitas 12ABCDEF* , Silvana Daher Costa 12ABDEF , Luís Gustavo Modelli de Andrade 3CDEF , Celi Melo Girão 2BCEF , Paula Frassinetti C.B.C. Fernandes 4DEF , Claudia Maria Costa de Oliveira 24DEF , Ronaldo de Matos Esmeraldo 2ADEF

DOI: 10.12659/AOT.927010

Ann Transplant 2020; 25:e927010

Table 2 Recipient demographic and clinical characteristics.

SC groupN=103MP groupN=103P value
n(%)59 (57.3)58 (56.3)1.000
mean±SD45.9±15.039.9±18.20.011
mean±SD24.5±4.722.6±4.70.004
n (%)0.857
 Caucasian9 (8.7)11 (10.7)
 Mixed/Hispanic89 (86.4)86 (83.5)
 Afro-Brazilian5 (4.9)6 (5.8)
n (%)0.059
 Unknown29 (28.3)41 (39.8)
 Hypertension28 (27.2)27 (26.2)
 Diabetes18 (17.5)9 (8.7)
 Glomerulonephritis8 (7.8)6 (5.8)
 Urological16 (15.5)8 (7.8)
 PKD3 (2.9)10 (9.7)
 Other1 (1.0)2 (1.9)
n (%)19 (18.4)10 (9.7)0.108
median (IQR)35 (20–58)36 (18–60)0.937
n (%)9 (8.7)12 (11.7)0.646
median (IQR)0 (0–1.9)0 (0–17)0.360
median (IQR)0 (0–0)0 (0–0)0.804
n(%)3 (2.9)16 (15.5)0.003
median (IQR)3 (3–4)3 (3–4)0.299
mean±SD20.8±4.128.1±6.3
mean±SD20.8±4.115.8±6.2
mean±SDn.a12.3±5.7n.a
mean±SD36.0±12.336.6±9.50.690
n(%)101 (98.1)102 (99.0)1.000
SC – static cold; MP – machine perfusion; BMI – body mass index; ESRD – end-stage renal disease; KT – kidney transplant; PKD – polycystic kidney disease; PRA – panel reactive antibodies; DSA – donor specific antibodies; HLA – human leukocyte antigen; CIT – cold ischemia time; VAT – vascular anastomosis time; rATG – rabbit antithymocyte globulin; na – not applicable; IQR – interquartile range; SD – standard deviation.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358