03 November 2020: Original Paper
Comorbidity Burden May Be Associated with Increased Mortality in Patients with Severe Acute Liver Injury Referred for Liver Transplantation
Lindsey Steiner-Temnykh 1ABCDEF , Lara Dakhoul 2ABCDEF , James Slaven 3ACDE , Lauren Nephew 2BCDEF , Kavish R. Patidar 2BCDEF , Eric Orman 2BCDEF , Archita P. Desai 2BCDEF , Eduardo Vilar-Gomez 2BCDEF , Chandrashekhar Kubal 4BCDEF , Burcin Ekser 4BCDEF , Naga Chalasani 2ABCDEF , Marwan Ghabril 2ABCDEF*DOI: 10.12659/AOT.926453
Ann Transplant 2020; 25:e926453
Table 3 A comparison of individual comorbidities in patients surviving hospitalization vs. dying or undergoing liver transplantation within 30 days of hospitalization for acute liver injury. Data are shown as number (percentage).
| OverallN=136 | Hospitalization or 30-day survivorn=76 | Died or transplant within 30 daysn=60 | P-value | |
|---|---|---|---|---|
| Diabetes without complications n (%) | 13 (10) | 8 (10) | 5 (8) | 0.9 |
| Diabetes with complications n (%) | 6 (4) | 3 (4) | 3 (5) | |
| Peptic ulcer disease n (%) | 16 (12) | 7 (9) | 9 (15) | 0.3 |
| Chronic pulmonary disease n (%) | 15 (11) | 11 (14) | 4 (7) | 0.15 |
| Liver disease (mild) n (%) | 28 (13) | 7 (9) | 11 (18) | 0.12 |
| Solid tumor – localized n (%) | 6 (4) | None | 6 (10) | 0.02 |
| Solid tumor – metastatic n (%) | 2 (1) | 1 (1) | 1 (2) | |
| Stroke n (%) | 6 (4) | 5 (7) | 1 (2) | 0.2 |
| Congestive heart failure n (%) | 6 (4) | 3 (4) | 3 (4) | 0.8 |
| Myocardial infarction n (%) | 6 (4) | 5 (7) | 1 (2) | 0.2 |
| Connective tissue disease n (%) | 6 (4) | 2 (3) | 4 (7) | 0.3 |
| Renal disease (moderate to severe) n (%) | 1 (1) | 1 (1) | None | 0.4 |
| Lymphoma n (%) | 1 (1) | None | 1 (2) | 0.3 |
| Acquired immunodeficiency syndrome n (%) | 1 (1) | None | 1 (2) | 0.3 |
| No patients had leukemia, hemiplegia, dementia or peripheral vascular disease. | ||||