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24 July 2020: Review Paper

Kidney Transplantation in the Times of COVID-19 – A Literature Review

Ashraf Imam ACDEF** , Sadi A. Abukhalaf ABCEF* , Riham Imam BCD , Samir Abu-Gazala AEF , Hadar Merhav ACD** , Abed Khalaileh ABCEF**

DOI: 10.12659/AOT.925755

Ann Transplant 2020; 25:e925755

Table 6 Clinical characteristics of the 58 reported kidney transplant patients who encountered covid-19 compared with previous published studies.

VariableThis studyAkalin et al. [47]Alberici et al. [48]CUKTP [49]Pooled (mean)
Number of patients58362015129
Age (mean)52.69595154.2
Sex
 Male75.9%72%80%67%73.7%
 Female24.1%28%20%33%26.2%
Kidney transplant years age (mean)7.681348.2
Type of donor
 Deceased41.2%75%80%65.4%
Comorbidities
 HTN68.9%94%85%82.6%
 DM36.2%69%15%40%
 CAD10.3%17%15%14%
Clinical presentation
 Fever84.5%58%100%87%82.3%
 Cough70%53%50%60%58%
 SOB56.9%44%5%27%33.2%
 Fatigue34.5%27%30.7%
 Myalgia15.5%36%5%13%17.3%
 Vomiting6.9%7%6.9%
 Diarrhea17.2%22%20%19.7%
 Sore throat5.2%10%7.6%
Laboratory
White cell count
 Mean per l (×10)65.35.44.85.37
 Leukopenia (22.8%21%21.9%
Lymphocyte count
 Mean per l (×10)0.60.61.10.80.77
 Lymphopenia (79%79%79%
Initial C-reactive protein (CRP)
 Mean497.94910452.4
 High CRP (>5 mg/dl)97.2%46%71.6%
Initial serum Creatinine (Cr)
 Mean1.91.81.85
 AKI28.2%40%34.1%
Initial D-dimer
 Mean10151020279771.3
 High D-dimer (>500 μg/L)72.7%57%64.8%
Initial lactate dehydrogenase (LDH)
 Mean266.5336231275277
 High LDH (>225 U/l)69.2%36%52.6%

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358