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13 October 2020: Original Paper

Pediatric Liver Transplantation for Alagille Syndrome: Anesthetic Evaluation and Perioperative Management

Wen-He Yang 1ABF* , Liang Zhang 1ABCDEF* , Fu-Shan Xue 1ADG* , Azmat Riaz 2EF , Zhi-Jun Zhu 345ADG*

DOI: 10.12659/AOT.924282

Ann Transplant 2020; 25:e924282

Table 4 Postoperative surgical complications and re-operations in pediatric AGS and BA recipients.

VariablesAGS (n=11)BA (n=98)P-value
Age (mo)23.5 (12.0–73.0)30.9 (10.3–73.3)0.007
Male gender (%)8 (72.7)54 (55.1)0.345
Height (cm)82.0 (71.5–102.0)70.0 (65.4–90.3)0.038
Weight (kg)8.5 (7.5–15)8.5 (7.0–13.3)0.466
Z Score* −2.69 (−3.49 – −1.31)−1.18 (−2.30 – −0.13)0.015
PELD score9 (3–15)10 (−3–21)0.759
Preoperative history of abdominal operation (%)9 (81.8)90 (91.8%)0.265
Living-related donor (%)8 (72.7)75 (76.5)0.722
Partial graft (%)10 (90.9)78 (79.6)0.687
Graft weight (g)267 (226–317)259 (210–326)0.644
GRWR (%)2.68±0.912.92±0.960.432
Surgical complications6 (54.5)22 (22.4)0.031
Re-operations (%)5 (45.5)15 (15.3)0.028
* Height for age Z score (Data form Chinese Center for Disease Control and Prevention).
AGS – Alagille syndrome; BA – biliary atresia; GRWR – graft-to-recipient weight ratio; LT – liver transplantation; PELD – Pediatric End-stage Liver Disease.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358