17 July 2020: Original Paper
Kidney Transplantation and “Sex Mismatch”: A 10-Year Single-Center Analysis
Karol Graňák 1ABCDE , Lea Kováčiková 1ABC , Petra Skalová 1AB , Matej Vnučák 1BDE , Juraj Miklušica 1ABCD , Ľudovít Laca 1ABC , Marián Mokáň 2FG , Ivana Dedinská 1ACEF*DOI: 10.12659/AOT.921117
Ann Transplant 2020; 25:e921117
Table 3 Group characteristics – male donor.
| Male donor (n=162) | Male recipient n=105 | Female recipient n=57 | P value |
|---|---|---|---|
| Age of the donor (years) | 45.7±15.6 | 40.5±14.7 | |
| BMI of the donor (kg/m2) | 25±3.6 | 24.8±4.5 | 0.7580 |
| ECD donor (%) | 31.4 | 17.5 | 0.0564 |
| eGFR at the time of procurement (ml/min) | 86±29.1 | 88±44 | 0.7291 |
| QVPU before procurement (g/sampling) | 0.8±0.5 | 1.2±0.8 | |
| Age of the recipient (years) | 47.9±11.7 | 47.6±10.7 | 0.8727 |
| CIT (min) | 612±275 | 637±346 | 0.6153 |
| DGF (%)* | 10.5 | 10.5 | 1.0000 |
| BMI of the recipient (kg/m2) | 25.6±3.8 | 25.5±3.8 | 0.8731 |
| Induction: basiliximab/daclizumab (%) | 60.0 | 63.2 | 0.6908 |
| Induction: thymoglobulin (%) | 32.4 | 17.5 | |
| Induction: None (%) | 7.6 | 19.3 | 0.0275 |
| Tacrolimus (%) | 83.8 | 75.4 | 0.1959 |
| PRA (%) | 3.7±1.9 | 2.4±1.1 | |
| Mismatch A | 1±0.9 | 1.1±0.6 | 0.4529 |
| Mismatch B | 1.1±0.7 | 1±0.7 | 0.3685 |
| Mismatch DR | 1.1±0.8 | 1.3±0.6 | 0.1007 |
| Creatinine D7 (μmol/l) | 227±189 | 196±154 | 0.2901 |
| Creatinine M1 (μmol/l) | 169±72 | 132±56 | |
| Creatinine M3 (μmol/l) | 161±50 | 130±29 | |
| Creatinine M6 (μmol/l) | 156±55 | 120±26 | |
| Creatinine Y1 (μmol/l) | 131±55 | 115±26 | |
| Creatinine Y3 (μmol/l) | 128±56 | 113±22 | 0.0541 |
| Creatinine Y5 (μmol/l) | 135±40 | 117±24 | |
| eGFR M1 (ml/min) | 43.2±12.7 | 43±13 | 0.9245 |
| eGFR M3 (ml/min) | 43.6±13.9 | 42±12.3 | 0.4678 |
| eGFR M6 (ml/min) | 46±15.5 | 45.5±11.8 | 0.8321 |
| eGFR R1 (ml/min) | 50±15.7 | 47.9±13.2 | 0.3921 |
| eGFR R3 (ml/min) | 50.5±14.7 | 47.5±10.5 | 0.1749 |
| eGFR R5 (ml/min) | 51.1±13.3 | 45.3±10.2 | |
| Acute rejection in anamnesis (%)** | 22.9 | 17.5 | 0.4218 |
| KT – kidney transplantation; BMI – body mass index; ECD – expanded criteria donors; eGFR – estimated glomerular filtration rate (according to CKD/EPI formula); QVPU – quantitative proteinuria; CIT – cold ischemia time; DGF – delayed graft function; D – day; M – month; Y – year. * Needed dialysis treatment in the first week after kidney transplantation; ** follow up: 1 year. | |||