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Medical Science Monitor Basic Research


eISSN: 2329-0358

An Alternative Surgical Technique of Native Hepatectomy in Liver Transplantation

Maogen Chen, Weiqiang Ju, Xiaohong Lin, Yinghua Chen, Qiang Zhao, Zhiyong Guo, Xiaoshun He, Dongping Wang

Organ Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China (mainland)

Ann Transplant 2021; 26:e929259

DOI: 10.12659/AOT.929259

Available online: 2021-02-10

Published: 2021-03-23


BACKGROUND: Orthotopic liver transplantation has become the procedure of choice for end-stage liver disease. There are 3 commonly used methods of vena cava anastomosis. Here, we report a new technique for native hepatectomy.
MATERIAL AND METHODS: The data of 12 patients who underwent orthotopic liver transplantation using a new surgical technique were retrospectively collected for analysis. The new separation and reconstruction surgical technique mainly involved the second portal isolation and hepatectomy that followed. We performed recipient liver resection without the occlusion of the inferior vena cava, which was then followed by classic, piggyback, modified piggyback, or side-to-side orthotopic liver transplantation. The graft function index and complications were collected after transplantation.
RESULTS: The length of the anhepatic phase was 30.92±9.1 min. Alanine transaminase (ALT) levels were 138 to 2027 U/L, with a median of 361.5 U/L. The ALT levels of all patients gradually decreased to normal levels 7 to 10 days after surgery. Only 2 recipients had elevated levels of ALT higher than 1000 U/L. Four of 12 patients did not require red blood cell transfusion during surgery. Four patients appeared to have early allograft dysfunction, while others recovered smoothly.
CONCLUSIONS: This new surgical technique may shorten the anhepatic phase and decrease blood loss volume, aiding the success of liver transplant surgery. It can be used for most patients and does not increase the risk of complications or impair prognosis.

Keywords: Hepatectomy, Liver Transplantation, Surgical Procedures, Operative