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eISSN: 2329-0358

A Single-Center Experience with an Intensivist-Led Brain-Dead Donor Management Program

Jin Park, Na Rae Yang, Young-Joo Lee, Kyung Sook Hong

Department of Neurology and Critical Care Medicine, Ewha Womans University College of Medicine, Seoul, South Korea

Ann Transplant 2018; 23:828-835

DOI: 10.12659/AOT.912025

Available online:

Published: 2018-12-04

BACKGROUND: The aim of this study is to report our experience of brain-dead donor management by a dedicated intensivist who had wide experience in treatment of hemodynamically unstable patient and to suggest a role for intensivists in organ donation.
MATERIAL AND METHODS: The management of brain-dead donors was performed by experienced intensivists. The hospital medical records and data from the Korean Network of Organ Sharing from August 2013 to December 2016 were reviewed retrospectively.
RESULTS: Fifty-four brain death patients (3.2% of KONOS nationwide data) donated organs in our institution during 41 months. Dedicated intensivists managed deceased patients for the whole duration (2.81±1.21 days) of management, not only with conservative therapies like fluid resuscitation, vasopressor, or hormonal replacement, but also with pulmonary artery catheter insertion for cardiac output monitoring (n=47, 87.0%) and continuous renal replacement therapy (n=22, 40.7%). The number of donors increased each year. The mean number of retrieved organs in each deceased donor was 3.98±1.55, more than the national average (3.26) and comparable to the higher level among the recent worldwide data. The number of donations by organ was: 23 hearts (4.9% of nationwide data), 17 lungs (7.5% of nationwide data), 102 kidneys (3.3% of nationwide data), 47 livers (3.1% of nationwide data), 6 pancreases (2.9% of nationwide data), 1 pancreatic duct (11.1% of nationwide data), and 1 small intestine (12.5% of nationwide data).
CONCLUSIONS: Management by dedicated intensivists will improve not only the number of actual organ donors, but also the number of harvested organs.

Keywords: Brain Death, Intensive Care, Organ Transplantation, Tissue and Organ Procurement