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Medical Science Monitor Basic Research


eISSN: 2329-0358

Complications and Near-Miss Events After Hepatectomy for Living-Related Liver Donation: An Italian Single Center Report of One Hundred Cases

Salvatore Gruttadauria, Duilio Pagano, Ioannis Petridis, Sergio Li Petri, Alessandro Tropea, Giovanni B. Vizzini, Angelo Luca, Bruno G. Gridelli

Department for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation, Abdominal Surgery and Organ Transplantation Unit, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (IRCCS-ISMETT), Palermo, Italy

Ann Transplant 2016; 21:596-601

DOI: 10.12659/AOT.899662

Available online: 2016-09-22

Published: 2016-09-22


BACKGROUND: In healthy individuals, such as liver living donors, potential complications may occur during surgery. Reporting such complications and near-miss events is mandatory to improve living donor management and safety.
MATERIAL AND METHODS: This retrospective study was performed on a prospective database with the aim of providing a brief analysis of the perioperative, medium-term, and long-term complications, and the near-miss events in a single center series of 100 consecutive liver resections for adult-to-adult living-donor liver transplantation.
RESULTS: Only 23.3% of potential living donors underwent surgery. No living donor mortality was reported; 29 patients (29%) experienced at least one complication. Five patients developed mild long-term dysfunction; two aborted hepatectomies, and there were two near-miss events reported.
CONCLUSIONS: A strategy for an accurate assessment of living donor complications and strict selection criterion cannot be overemphasized, as well as the need to continuously update center patient outcome reports.

Keywords: Liver Transplantation, Living Donors, Morbidity