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Medical Science Monitor Basic Research

AmJCaseRep
MedSciTechnol

eISSN: 2329-0358

Technical Refinement of Hepatic Vein Reconstruction in Living Donor Liver Transplantation Using Left Liver Graft

Mitsuhisa Takatsuki, Akihiko Soyama, Masaaki Hidaka, Ayaka Kinoshita, Zhassulan Baimakhanov, Tota Kugiyama, Tomohiko Adachi, Amane Kitasasto, Tamotsu Kuroki, Susumu Eguchi

Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

Ann Transplant 2015; 20:290-296

DOI: 10.12659/AOT.893136

Available online: 2015-05-25

Published: 2015-05-25


#893136
#893136

BACKGROUND: In adult living donor liver transplantation (LDLT), left liver graft is generally safer for the donor. The aim of this study was to demonstrate a technical refinement for achieving sufficient outflow using left liver graft.
MATERIAL AND METHODS: Forty-seven cases using left liver were divided into 2 groups according to the procedures of hepatic vein reconstruction: the side-clamp group (21 cases), and the cross-clamp group (26 cases), to sufficiently enlarge the diameter of the hepatic vein with excising the inferior vena cava (IVC).
RESULTS: The liver function tests at 7 days after LDLT were not significantly different between the 2 groups, but the median amount of ascites was significantly greater in the side-clamp group (1250 ml; range, 484–3690) than in the cross-clamp group (582 ml; 190–2785). When we selected the patients with the ratio of graft weight to recipient standard liver volume less than 30%, the 1-year patient survival after transplantation was significantly better in the cross-clamp group than in the side-clamp group (90% in cross-clamp group vs. 71% in side-clamp group, P<0.05).
CONCLUSIONS: In conclusion, hepatic vein reconstruction with cross-clamping of the IVC can secure a sufficient outflow in LDLT using left liver graft.

Keywords: Hepatic Veins, Liver Transplantation, Living Donors



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