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26 September 2012

Pregnancy after living related liver transplantation – a report of two cases

Bożena Kociszewska-NajmanABDEF, Bronisława PietrzakABDEF, Zoulikha Jabiry-ZieniewiczABDF, Natalia MazanowskaBEF, Mirosław WielgośAF

DOI: 10.12659/AOT.883466

Ann Transplant 2012; 17(3): 120-125

Abstract

Background: Living related liver transplantation (LRLT) is currently the only available alternative to orthotopic liver transplantation that is of use in children with acute liver failure. There are reports of long-term survival in liver graft recipients who had been transplanted in childhood. In female patients of reproductive age it may also mean ability to conceive.
Case Report: We report 2 cases of successful pregnancies in women after living related liver transplantation. During the 6-month follow-up, no obstetric complications during pregnancy, delivery and postpartum period, and no deterioration of graft function were noted. The neonates were delivered full-term in good general condition, with no signs of intrauterine hypotrophy, congenital malformations or infection, and their psycho-motor development is perfectly normal.
Conclusions: These 2 cases of pregnancies with favorable perinatal outcomes in women after living related liver transplantation, who delivered in our Department with no deterioration of graft function, may be regarded as evidence of full recovery in women after the LRTL procedure.

Keywords: living related liver transplantation, Pregnancy, neonatal outcome

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358