Catheter-directed thrombolysis with tPA to restore renal function after iliac venous thrombosis post-renal transplantation
Courtney Fulton, Tom McGregor, Tom L. Forbes, David Peck, Patrick P.W. Luke
Ann Transplant 2011; 16(1): 61-65
Available online: 2011-03-23
Background: Successful salvage of a failing renal allograft secondary to compromised venous outflow from acute deep venous thrombus (DVT) has not been reported in the post-operative setting.
Case Report: We present a case of acute DVT extending from the popliteal vein to the bifurcation of the inferior vena cava leading to renal allograft dysfunction in the post-operative period. The allograft was successfully salvaged with catheter directed thrombolysis of the DVT with tPA through the ipsilateral popliteal vein over a 48 hr period.
Conclusions: Post-operative renal transplant dysfunction secondary to iliac vein thrombosis can be successfully treated with catheter-directed thrombolysis using tPA.
Keywords: Venous thrombosis, renal transplantation, thrombolysis