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21 May 2009

Living donor kidney transplantation (LDKT) – 10 years single centre experience

A Chamienia, A Dębska-Ślizień, B Rutkowski, G Moszkowska, D Zadrożny, Z Śledziński

Ann Transplant 2009; 14(1): 59-59 :: ID: 880522

Abstract

Background: Kidney transplantation (KT) is considered the best treatment option for most patients with chronic renal failure. Available data show that living donor KT (LDKT) is a viable option in transplantation characterized by better short and long term results. In Poland number of LDKT is very low and accounts for between 2 and 3% of all KT performed.
Material/Methods: We present here 10 years of LDKT experience in a single centre between 1999 and 2009. There were 23 LDKT performed during this period, which accounts for 3.3% of all KT in this period.
Results: Most (83%) were living related donor KT. Mean recipient's age was
33±11 years and mean donor's age was 48±7 years. Most donors were women (15-65%). In most but 3 cases the LDKT was a fi rst transplant. Mean number of HLA class I and II mismatches was 3.2±1.3. Mean cold ischemia time was 167±51 min. and warm ischemia time 37±36 min. 4 recipients (17.4%) received ATG induction and 3 (13%) daclizumab induction. 34% of recipients were placed on cyclosporin based immunosuppression and remaining 66% on tacrolimus. 59% received mycophenolate mofetil. All recipients received steroids. Delayed graft function was observed in 3 cases and in 4 cases acute rejection was diagnosed. One year patient's and graft's survival were both 100%. Five year patient's and graft's survival were 100% and 93%, respectively. The mean serum creatinine levels at hospital discharge, 6 months, 1 and 5 years after KT were 1.91±0.4, 1.7±0.3, 1.55±0.4 and 1.64±1.09 mg/dl, respectively.
Conclusions: Our results confi rm excellent outcomes reported previously in
LDKT. This form of KT should be actively promoted in our country.

Keywords: Kidney Transplantation, Living Donors

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358