Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Urinary iodine concentrations should be monitored to diagnose some thyroid gland diseases in heart transplant recipients

E Wozniak-Grygiel, A Cichoracka, S Zeglen, M Zakliczynski, M Zembala

Ann Transplant 2009; 14(1): 62-62 :: ID: 880424


Background: According to WHO iodine excreted with urine is a measure
of its supply. Due to International Council for Control of Iodine Deficiency
Disorders (ICCIDD), the urinary iodine (UI) should be above 100 μg I per 1
L of urine. The moderate iodine deficiency (MID) occurs when UI is from 50
to 100 μg/L and the severe deficiency (SID) when UI is below 50 μg/L.
Material/Methods: UI analysis in 32 heart transplant recipients (26 men and 6
women; mean age 50.4±12.6 yr) by modified PAMM method (the spectrophotometric measurement based on the Sandell-Kolthoff reaction). Results were evaluated and compared with thyroid stimulating hormone (TSH; μIU/mL), free triiodothyronine (FT3; pg/mL) and thyroxin (FT4; ng/dL). Hormones were measured using a Microparticle Enzyme Immunoassay (MEIA).
Results: The average UI in the whole group was 126.4±109.6. Unfortunately,
SID in 12 patients (37.5%) and MID in 4 of them (12.5%) was noted (mean UI: 17.0±9.6 and 79.5±5.6, respectively). In the rest 16 patients (50%) average UI was high and amounted 220.1±72.1. TSH, FT3 and FT4 in the whole group were in the normal range. However, FT4 values significantly differed when SID and MID-patients were compared to those with recommended UI (0.8±0.2 and 0.9±0.1 vs. 1.1±0.2, p<0.05; respectively). Decreased values of TSH in 5 patients (15.6%) and FT3 or FT4 in 6 (18.8%) were noted.
Conclusions: Measurements of urinary iodine in heart transplant recipients
together with thyroid gland hormones may be essential to monitoring and
preventing thyroid gland abnormalities.

Keywords: Heart Transplantation


In Press

06 May 2022 : Original article  

Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of D...

Ann Transplant In Press; DOI: 10.12659/AOT.936293  

27 Apr 2022 : Review article  

A Systematic Review of the Literature on Chronic Kidney Disease Following Liver Transplantation

Ann Transplant In Press; DOI: 10.12659/AOT.935170  

Most Viewed Current Articles

29 Dec 2021 : Original article  

Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...

DOI :10.12659/AOT.933588

Ann Transplant 2021; 26:e933588

26 Jan 2022 : Review article  

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models

DOI :10.12659/AOT.934924

Ann Transplant 2022; 27:e934924

24 Jul 2020 : Review article  

Kidney Transplantation in the Times of COVID-19 – A Literature Review

DOI :10.12659/AOT.925755

Ann Transplant 2020; 25:e925755

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358