Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Results of kidney’s transplantation procured from expanded criteria donors

P Domagała, A Kwiatkowski, M Wszoła, J Czerwiński, Ł Panufnik, K Ostrowski, L Pączek, M Durlik, A Chmura

Ann Transplant 2009; 14(1): 54-54 :: ID: 880396

Abstract

Background: Kidney transplantation is the treatment of choice for patients with end-stage renal disease. Organ shortage is the main barrier to offer this treatment to all who need it. Using expanded criteria donor's (ECD) organs is one of the strategies for making more transplants available. Aim: The aim of this study was to assess the results of kidney transplantation procured from expanded criteria donors.
Material/Methods: One hundred and seventy two patients received cadaveric renal transplants between January 1st, 2006 and August 31st, 2008. Data on donors and recipients was collected. Patient and graft survival, as well as immediate, delayed and slow graft function were analysed. Kidney recipients' function was assessed by serum creatinine concentration and creatinine clearance according to Cockroft-Gault formula at seven days, 1, 3, 6, 12 and 24 months post transplantation. The follow-up was completed on November 30[sup]th[/sup], 2008.
Results: Average 1-year graft survival was 86.9% for the whole group and mean creatinine concentration was 1.58 mg/dl. One case of primary nonfunction was observed (0.6%). More than 25% of transplanted kidneys were harvested from ECD. There were no significant differences in patient's survival between recipients of standard criteria donor (SCD) and ECD organs. Graft's survival was higher in the SCD group than in the ECD group (one-year survival - 94.4% vs. 62.5%, p=0.004). There were no differences in the incidence of primary non function and delayed graft function between the groups. Recipients of ECD kidneys were more likely to have slow graft function (69.2% vs. 37.8%, p=0.033).
Conclusions: There is no significant difference in patient's survival between
recipients of kidney harvested from expanded and standard criteria donors.
Expanded criteria donor's kidneys have lower graft survival rates. There is no
significant difference in the incidence of delayed graft function between recipients of kidney harvested from expanded and standard criteria donors.

Keywords: Kidney Transplantation

Comments

In Press

06 May 2022 : Original article  

Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of D...

Ann Transplant In Press; DOI: 10.12659/AOT.936293  

27 Apr 2022 : Review article  

A Systematic Review of the Literature on Chronic Kidney Disease Following Liver Transplantation

Ann Transplant In Press; DOI: 10.12659/AOT.935170  

Most Viewed Current Articles

31 Dec 1969 : Original article  

Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...

DOI :10.12659/AOT.933588

Ann Transplant 2021; 26:e933588

31 Dec 1969 : Review article  

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models

DOI :10.12659/AOT.934924

Ann Transplant 2022; 27:e934924

31 Dec 1969 : Review article  

Kidney Transplantation in the Times of COVID-19 – A Literature Review

DOI :10.12659/AOT.925755

Ann Transplant 2020; 25:e925755

31 Dec 1969 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358