Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Initial experience with renal transplant artery stenosis angioplasty and stenting – it does not confirm antihypertensive or renal function benefit

R Kieszek, K Ostrowski, O Rowiński, M Durlik, A Chmura, M Geremek

Ann Transplant 2009; 14(1): 51-51 :: ID: 880385


Background: Transplant renal artery stenosis (TRAS) affects 1-25% of transplant recipients and may lead to allograft loss. The most common presentation is hypertension or elevated serum creatinine concentration (sC); frequently asymptomatic TRAS is seen on routine Doppler US. Objective: To evaluate early results of transplant artery angioplasty in our first referrals from a transplant centre.
Material/Methods: 10 patients (7 male, 3 female, mean age 52.1 years) referred for hypertension (n=3) or elevated sC at various periods post-transplant (4-41 months) were diagnosed with TRAS by Duplex Doppler. All patients underwent balloon angioplasty and 9 had primary stenting. Follow-up ranged from 2 to 21 months with evaluation of arterial blood pressure (ABP), sC, creatinine clearance and the number of antihypertensive drugs taken.
Results: Four patients experienced re-stenosis of the renal transplant artery, three required re-intervention for refractive hypertension. No significant differences were observed pre- and post angioplasty in mean ABP (106.27 vs. 105.36), sC (2.43mg% vs. 2.28m%), creatinine clearance (44.62 vs. 46.9 mL/min) or the number of antihypertensive drugs (3.1 vs. 3.4). There were no graft losses or deaths, dilatation and stent placement were satisfactory at primary angiography in all patients.
Conclusions: Limited experience with a new group of patients does not confirm encouraging results from the other centres in treating hypertension and deteriorating renal graft function secondary to graft's arterial stenosis. A greater number of patients may help to evaluate the impact of endovascular intervention on the long-term graft function, which may be influenced by other factors, such as chronic allograft nephropathy, immunosuppressant  nephrotoxicity etc. Satisfactory angiography result is not necessarily reflected by the clinical course.

Keywords: Kidney Transplantation


In Press

06 May 2022 : Original article  

Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of D...

Ann Transplant In Press; DOI: 10.12659/AOT.936293  

27 Apr 2022 : Review article  

A Systematic Review of the Literature on Chronic Kidney Disease Following Liver Transplantation

Ann Transplant In Press; DOI: 10.12659/AOT.935170  

Most Viewed Current Articles

31 Dec 1969 : Original article  

Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...

DOI :10.12659/AOT.933588

Ann Transplant 2021; 26:e933588

31 Dec 1969 : Review article  

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models

DOI :10.12659/AOT.934924

Ann Transplant 2022; 27:e934924

31 Dec 1969 : Review article  

Kidney Transplantation in the Times of COVID-19 – A Literature Review

DOI :10.12659/AOT.925755

Ann Transplant 2020; 25:e925755

31 Dec 1969 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358