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21 May 2009

Complications after transplantation of kidney procured from the expanded criteria donors

P Domagała, A Kwiatkowski, M Wszoła, J Czerwiński, K Cybula, J Trzebicki, K Ostrowski, A Chmura

Ann Transplant 2009; 14(1): 50-51 :: ID: 880384

Abstract

Background: Organ shortage is the main barrier for kidney transplantation. In order to maximize organ utilization, expanded criteria donor's organs have been used increasingly. Expanded criteria donor is defined as a donor older than 60 years or a donor older than 50 years with at least two of the following: hypertension, stroke as a cause of death or serum creatinine greater than 1.5 mg/dl. Aim: The aim of this study was to assess the number of complications after transplantation of kidneys harvested from the expanded criteria deceased donors in comparison to organs retrieved from standard criteria deceased donors.
Material/Methods: One hundred and seventy two patients received cadaveric renal transplants between January 1st,2006 and August 31st,2008. Data on donors and recipients was collected. Patient and graft survival as well as immediate, delayed and slow graft function were analysed. Kidney function was assessed by serum creatinine concentration and creatinine clearance according to Cockroft-Gault formula at seven days, 1, 3, 6, 12 and 24 months post transplantation. The follow-up was completed on November 30[sup]th[/sup], 2008. All patients were followed-up for three to thirty five months.
Results: Average 1-year graft survival was 86.9% for the whole group and mean creatinine concentration was 1.58 ml/dl. One case of primary nonfunction was observed (0.6%). More than 25% of transplanted kidneys were harvested from ECD. There were no significant differences in postoperative complications between recipients of standard criteria donor's (SCD) and ECD organs (Table).
Conclusions: Recipients of expanded criteria donor's kidneys experience
a comparable rate of complications to recipients of standard criteria donor's kidneys.

Keywords: Kidney Transplantation

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358