M Zukowski, R Bohatyrewic, J Biernawska, K Katarzyna, M Zegan, M Ostrowski, I Sulikowski, K Kedzierska
Ann Transplant 2009; 14(1): 48-48
Available online: 2009-05-21
Background: The quality of the transplanted kidney depends on many factors
that may debilitate its function, what can result in the necessity of haemodialysis treatment in the post operative period. Aims: Determining the inï¬‚uence of selected risk factors on the duration and number of haemodialysis post transplantation.
Material/Methods: Hemodynamic data was obtained from a group of 146
multi-organ donors. Group of 232 kidney transplant recipients was included in this study. Inï¬‚uence of the following factors on the duration and number of haemodialysis sessions in the postoperative period was analyzed: PRA value, HLA matching, length of haemodialysis prior to transplantation, donor's age and risk factors: MAP, CVP, PCWP, SVRI, dopamine infusion and CIT. Shapiro-Wilk, Kruskal-Wallis, Chi2 with the Yates correction and Fisher tests and analysis of correlation and regression were used, p=0.05.
Results: Decreased duration and fewer dialysis sessions were observed in the recipients, who had their kidney transplanted from the donors with MAP >70 mmHg, PCWP >12 mmHg and dopamine infusion <10 μg/kg/min. Positive correlation was observed between BSA, dopamine dose infusion, recipient's
age, length of haemodialysis prior to transplantation and the duration of the haemodialysis required post transplant.
Conclusions: 1) Increased MAP and PCWP in the donor both have a major inï¬‚uence on decreasing the duration of haemodialysis of kidney recipient post transplantation; 2) Increased BSA, dopamine dose infusion requirements in the donor, age and duration of haemodialysis before transplantation substantially prolong the duration of haemodialysis post transplantation.
Keywords: Kidney Transplantation, Organ Procurement