21 May 2009
Clotting disorder in the liver transplant recipients
D Porowski, M Sejdak, M Niemczyk, J Ziółkowski, A Chmura, L PączekAnn Transplant 2009; 14(1): 43-43 :: ID: 880354
Abstract
Background: The function of many organs depends on the time of achieving full liver efficiency after transplantation. The aim of the study was to estimate the influence of the transplanted liver's efficiency on selected coagulation parameters as well as the analysis of other factors infl uencing clotting disorder in the liver transplant recipients.
Material/Methods: Fifty-one patients after liver transplantation performed in 2002 were included into the study. The results of serum biochemistry, coagulation and blood cell count were retrospectively analysed at the time of liver transplantation and after 1, 2, and 5 years post-transplant. Also immunosuppressive regimen, presence of splenomegaly, and anticoagulation agents were taken into consideration.
Results: Improvement of transplanted liver function significantly influences the coagulation parameters in patients in the first year post-transplant. The statistically significant dependences were found between INR and albumin level (p=0.0000007), PT and ALT (p=0.00000006), and aPTT and ALT (p=0.00002). Factors not connected directly with transplanted liver efficiency (splenomegaly, immunosuppressive regimen and infections) are more important in the late period after transplantation.
Keywords: Liver Transplantation, clinical outcome
In Press
06 May 2022 : Original article
Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of D...Ann Transplant In Press; DOI: 10.12659/AOT.936293
27 Apr 2022 : Review article
A Systematic Review of the Literature on Chronic Kidney Disease Following Liver TransplantationAnn Transplant In Press; DOI: 10.12659/AOT.935170
Most Viewed Current Articles
31 Dec 1969 : Original article
Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...DOI :10.12659/AOT.933588
Ann Transplant 2021; 26:e933588
31 Dec 1969 : Review article
Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive ModelsDOI :10.12659/AOT.934924
Ann Transplant 2022; 27:e934924
31 Dec 1969 : Review article
Kidney Transplantation in the Times of COVID-19 – A Literature ReviewDOI :10.12659/AOT.925755
Ann Transplant 2020; 25:e925755
31 Dec 1969 : Case report
Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...DOI :10.12659/AOT.935860
Ann Transplant 2022; 27:e935860