The inﬂuence of the recipient’s body weight on the probability to obtain a heart transplant – POLKARD HF registry
T Zieliński, M Sobieszczańska-Małek, M Piotrowska, A Browarek, M Zembala, M Zakliczyński, J Sadowski, P Przybyłowski, K Roguski, J Różański, A Parulski, J Korewicki
Ann Transplant 2009; 14(1): 30-30
Available online: 2009-05-21
Background: In the selection process of heart recipient multiple factors are considered. The aim was to analyse the inï¬‚uence of the body weight of the adult heart recipient on the chance to obtain a heart transplant. In the POLKARD HF registry 658 patients (pts),(578 men), age 49±11.6 years, mean weight 77.5±15 kg were registered on the waiting list as potential heart transplant recipients. Transplanted (T) and not transplanted (NT) patients were compared. The frequencies of transplantation and probability of not having a transplant Kaplan Meier curves were analyzed (log rank test) stratified by recipient's body weight. Significance of recipient's weight on heart transplant probability was tested with a multivariate proportional hazard Cox model.
Results: 325 pts had heart transplantation (OHT) during follow-up. 60% recipients weighing below 80 kg were transplanted compared with 37% weighing 80 kg or more (p<0.0001). Only weight (p<0.00001) and age (p<0.05)were significant in the multivariate model. Survival curves before OHT were similar between pts stratified by body weight. The chance to receive a heart transplant decreased by every 10 kg of body weight increase, in pts heavier that 80 kg. The lowest probability of OHT was seen in pts with a body weight exceeding 100 kg (30%)
Conclusions: 1. In adult heart transplant candidates the chance to receive a
heart transplant significantly decreases if the recipient' s weight exceeds 80 kg.
2. Patients with a body weight more than 110 kg had a poor chance to receive
a heart transplant.
Keywords: Heart Transplantation