Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Liver regeneration in 120 consecutive living-related liver donors

K Zieniewicz, R Paluszkiewicz, P Kalinowski, P Hevelke, I Grzelak, R Pacho, M Krawczyk

Ann Transplant 2009; 14(1): 29-29 :: ID: 880305


Background: Living related liver transplantation for paediatric patients has
become an acceptable, low risk treatment option. The aim of this study was to assess the extent of the donor's liver regeneration.
Material/Methods: Between October 1999 and January 2008 120 living related donors were operated on and 109 grafts consisting of II, III segments and 11 grafts consisting of II, III and IV segments were harvested. Volumetric assessment of the donor's liver and selected segments was performed using computed tomography. After procurement every graft was weighed. Seven and 30 days, and 12 months after the operation donor's liver remnant was evaluated for differences in volume.
Results: Significant correlation between liver graft mass and its volume assessed with computed tomography was found (r=0.781; p<0.05). Twelve months after procurement average regeneration index was significantly higher in donors of segments II, III, IV (139.11±22.88%) versus donors of segments II and III  (108.83±17.25%) (p<0.05). Conclusions: Liver regeneration after procurement of selected liver segments from the living donors is a consistent finding and computed tomography is an accurate imaging modality to track changes in liver volume. This study shows positive correlation between the size of liver graft and regeneration of liver remnant in the donor

Keywords: Liver Transplantation, Living Donors, clinical outcome


In Press

06 May 2022 : Original article  

Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of D...

Ann Transplant In Press; DOI: 10.12659/AOT.936293  

27 Apr 2022 : Review article  

A Systematic Review of the Literature on Chronic Kidney Disease Following Liver Transplantation

Ann Transplant In Press; DOI: 10.12659/AOT.935170  

Most Viewed Current Articles

31 Dec 1969 : Original article  

Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...

DOI :10.12659/AOT.933588

Ann Transplant 2021; 26:e933588

31 Dec 1969 : Review article  

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models

DOI :10.12659/AOT.934924

Ann Transplant 2022; 27:e934924

31 Dec 1969 : Review article  

Kidney Transplantation in the Times of COVID-19 – A Literature Review

DOI :10.12659/AOT.925755

Ann Transplant 2020; 25:e925755

31 Dec 1969 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358