Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Reduction of biliary complication rate using continuous suture and no biliary drainage for duct-to-duct anastomosis in whole-organ liver transplantation

R Klęk, M Post, K Jarosz, J Butkiewicz, J Lubikowski, S Zeair, M Wójcicki

Ann Transplant 2009; 14(1): 29-29 :: ID: 880303


Background: Biliary complications (BCs) following liver transplantation (LTx) are related to various factors including surgical technique and the use of biliary drains for duct-to-duct (DD) anastomosis. We report the influence of changing the surgical technique on BCs in our centre.
Material/Methods: The incidence, treatment and outcome of BCs following adult LTx (between February 2002 and February 2007) with DD anastomosis were analyzed. There were 101 LTx with DD anastomosis in 99 patients, of  which 84 were analyzed. Recipients, who died within 30 days of LTx without  evidence of BCs and one patient with biliary strictures secondary to hepatic artery
thrombosis, were excluded. Until late-2004, DD anastomosis with  interrupted sutures over an external biliary drain (DD/BD) was performed in 35 patients. Following this, no biliary drain was used for DD anastomosis (DD/non-BD) created routinely with a continuous suture in 49 patients.
Results: DD anastomosis with interrupted sutures over a biliary drain was  associated with a higher incidence of both total (31% vs. 8%; P=0.008) and late (>30 days) BCs (20% vs. 2%; P=0.008). All biliary leaks in patients with  DD/BD reconstruction occurred from the exit site of the drain following its  removal. No statistically significant differences were found when incidence of biliary strictures and the necessity of surgical intervention were compared.  One patient died due to a biliary complication.
Conclusions: DD anastomosis performed with a continuous suture technique and no external biliary drainage reduces the incidence of BCs after LTx.

Keywords: Liver Transplantation


In Press

06 May 2022 : Original article  

Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of D...

Ann Transplant In Press; DOI: 10.12659/AOT.936293  

27 Apr 2022 : Review article  

A Systematic Review of the Literature on Chronic Kidney Disease Following Liver Transplantation

Ann Transplant In Press; DOI: 10.12659/AOT.935170  

Most Viewed Current Articles

31 Dec 1969 : Original article  

Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...

DOI :10.12659/AOT.933588

Ann Transplant 2021; 26:e933588

31 Dec 1969 : Review article  

Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models

DOI :10.12659/AOT.934924

Ann Transplant 2022; 27:e934924

31 Dec 1969 : Review article  

Kidney Transplantation in the Times of COVID-19 – A Literature Review

DOI :10.12659/AOT.925755

Ann Transplant 2020; 25:e925755

31 Dec 1969 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358