21 May 2009
A comparison of transplant outcomes in peritoneal and hemodialysis patients – a paired kidney analysis
A Dębska-Ślizień, , W Wołyniec, G Moszkowska, D Zadrozny, A Milecka, B RutkowskiAnn Transplant 2009; 14(1): 26-26 :: ID: 880293
Abstract
Background: Studies examining the effect of pre-transplant dialysis modality on graft and patient survival have given confl icting results. Therefore, we studied the effects of pre-transplant dialysis modality on the transplantation outcome. To minimize the donor variability and bias, a paired kidney analysis was used.
Material/Methods: From December 1994 to December 2005, 69 peritoneal dialysis (PD) (31 m, 48 f) patients received transplantation. PD constituted 12% of all kidney transplantations performed in our centre at that time. 50/69 PD patients (27 m, 23 f) aged from 14 to 64 (mean 39.9±12.4) years had their haemodialysis (HD) pair (34 m, 16 f) aged from 16 to 69 (mean 42.6±11.5) years.
Results: Studied groups (PD vs. HD) differed significantly with respect to duration of RRT before transplantation (19.7±20.4 vs. 35.5±50.7; p<0.05) months. The groups (PD vs. HD) did not differ significantly with respect to: number of mismatches, type of immunosuppressive protocol, one year patient survival (96% vs. 100%), and one-year graft survival (86% vs. 86%). PD vs. HD had lower incidence of delayed graft function (18% vs. 46%; p< 0.05) and acute rejection (22% vs. 30%), graft thrombosis was more commonly listed as a cause of graft failure in PD group, also all types of infections occurred more
frequently in PD patients (44% vs. 32%). Graft function estimated one year after transplantation applying creatinine concentration was similar in PD vs. HD group (1.57 mg/dl vs. 1.61 mg/dl). Conclusions. The outcome of RT is similar in patients coming from either PD or HD. Delayed graft function was less common in PD patients but this potential benefit appears to be counter-balanced by other factors with are associated with the graft loss
Keywords: Kidney Transplantation
In Press
06 May 2022 : Original article
Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of D...Ann Transplant In Press; DOI: 10.12659/AOT.936293
27 Apr 2022 : Review article
A Systematic Review of the Literature on Chronic Kidney Disease Following Liver TransplantationAnn Transplant In Press; DOI: 10.12659/AOT.935170
Most Viewed Current Articles
31 Dec 1969 : Original article
Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...DOI :10.12659/AOT.933588
Ann Transplant 2021; 26:e933588
31 Dec 1969 : Review article
Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive ModelsDOI :10.12659/AOT.934924
Ann Transplant 2022; 27:e934924
31 Dec 1969 : Review article
Kidney Transplantation in the Times of COVID-19 – A Literature ReviewDOI :10.12659/AOT.925755
Ann Transplant 2020; 25:e925755
31 Dec 1969 : Case report
Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...DOI :10.12659/AOT.935860
Ann Transplant 2022; 27:e935860