Serdar Yilmaz, Mark Nutley, Eero Taskinen, Timo Paavonen, Pekka Hayry
Ann Transplant 2000; 5(2): 37-43
Apart of death with functioning transplant, which is mostly related to cardiovascular complications, poor long-term survivalof renal transplants has been related to chronic rejection. In Dunn's series, the most common cause of kidney graft lossbeyond 2yearswas chronic rejection (36.2%), followed by noncompliance (27.6%), death with a functioning transplant (22%), and acute rejection (8.6%) . Ferguson reported an overall incidence of chronic kidney allograft rejection of 23% over a 3 to 10-year follow-up . Graft failure due to chronic rejection is the leading cause of the estimated yearly 6-12% graft loss after the first year . Chronic rejection does not affect patient survival,but it has a significant effect on the5-yeargraftsurvival...
Keywords: chronic rejection, Pathology, CADI