28 June 2005 : Review article
Ann Transplant 2005; 10(2): 5-9 :: ID: 16806
Summary: The innate immune processes proceeding in organ allografts and their contribution to acute and chronic rejection have been described. Ischemia/reperfusion phenomenon with damage of the endothelial and parenchymal cells and reaction of granulocytes and
macrophages as well as humoral factors including complement, coagulation factors, free radicals, nitrous oxide have an impact on late function of the transplanted organs. Participation of granulocytes and macrophages in acute allogeneic rejection is another example of the role of the innate system in transplant damage. Recurrent basic disease, diabetes, hyperlipidemia, adverse effects of immunosuppressive drugs in allograft recipients are factors evoking reaction of the innate system. Investigations of the innate immune system have shown an essential role, beside of the adaptive system stimulated by allogeneic mismatch, in organ graft rejection.
Keywords: innate immunity, adaptive immunity, Allotransplantation
20 Jan 2022 : Original articleImpact on Waitlist Outcomes from Changes in the Medical Eligibility of Candidates for Simultaneous Liver-Ki...
Ann Transplant In Press; DOI: 10.12659/AOT.934850
19 Jan 2022 : Original articleCarbohydrate Metabolism Disorders in Relation to Cardiac Allograft Vasculopathy (CAV) Intensification in He...
Ann Transplant In Press; DOI: 10.12659/AOT.933420
18 Jan 2022 : Original articlePLGA+Fe₃O₄+PFP Nanoparticles Drug-Delivery Demonstrates Potential Anti-Tumor Effects on Tumor Cells
Ann Transplant In Press; DOI: 10.12659/AOT.933246
Most Viewed Current Articles
29 Dec 2021 : Original articleEfficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...
Ann Transplant 2021; 26:e933588
22 Dec 2021 : Original articleComparison of Coronary Artery Calcium Scoring with Dobutamine Stress Echo for Detection of Coronary Artery ...
Ann Transplant 2021; 26:e934163
12 Jan 2022 : Original articleRisk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...
Ann Transplant 2022; 27:e934738