15 January 2004
Prognosis Model of Regeneration Processes at Application of Natural Bioimplants
L. I. Donchenko, V. G. Klimovitskii, S. V. Popov, A. V. StepuraAnn Transplant 2004; 9(1A): 88-91 :: ID: 15643
Abstract
Biomplantation is a current direction in advanced medicine. Development of various kinds of implantable biomaterials with given strength characteristics, preservation of vital biochemical properties with a low immunogenity and a high level inductivity of regenerative processes makes studies of biochemical reactions after implantation of biomaterials very pertinent. These will elucidate the peculiarities of regeneration processes at application of different kinds of bioimplantable materials. In this work we have studied the electrolyte exchange and enzyme activity after transplantation using natural materials. The content of macroelements and enzyme activity at auto- and allo-transplantations of Achilles’ tendon were comparatively investigated in thirty Chinchilla rabbits. We investigated blood sera for both groups of animals after tendon transplantations after 7, 14, 21, 45, and 90 days. It was revealed that after transplantation the blood serum sodium titre, amylase and acid phosphatase activities, which were baselined at an earlier time, are the informative data set for predicting the course of regeneration. Application of the developed algorithm in clinical conditions revealed a high prognosis accuracy (84%).
Keywords: Bioimplants, Prognosis of Regeneration, Electrolyte, Enzyme Activity
In Press
06 May 2022 : Original article
Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of D...Ann Transplant In Press; DOI: 10.12659/AOT.936293
Most Viewed Current Articles
29 Dec 2021 : Original article
Efficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...DOI :10.12659/AOT.933588
Ann Transplant 2021; 26:e933588
26 Jan 2022 : Review article
Recurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive ModelsDOI :10.12659/AOT.934924
Ann Transplant 2022; 27:e934924
24 Jul 2020 : Review article
Kidney Transplantation in the Times of COVID-19 – A Literature ReviewDOI :10.12659/AOT.925755
Ann Transplant 2020; 25:e925755
15 Mar 2022 : Case report
Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...DOI :10.12659/AOT.935860
Ann Transplant 2022; 27:e935860