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Medical Science Monitor Basic Research


eISSN: 2329-0358

Pregnancies in Renal Transplantation Recipients – Focus on Babies

N Basri, Al-Ghamdi, F Shaheen, Hejaili, Flaiw, J Qureshi, A Al-Khader

Ann Transplant 2004; 9(3): 65-67

ID: 10222

Available online: 2004-10-29

Published: 2004-10-29

We studied 113 pregnancies in 72 renal transplant recipients. The mean duration between the transplant operation and the first pregnancies was 19.9 months (1-72). This paper focuses on the findings in babies and their outcome. The male babies were 34% of the total. 28% of the babies were delivered vaginally and 72% by Caesarian section. It was noted that there was high incidence of preterm delivery in 64% of the pregnancies. The birth weights were also less than that observed in the general population. 84% was under 50th percentile for weight with 19% being under the 10th percentile. (Saudi growth chart, KACST) The mean hospital stay was 18 days (2-44). The Apgar score was less than 7 in only 10% of the cases and 10 in 50.9%. The incidence of congenital defects was low and no different than the general population (we encountered only 4 cases with minor defects). Despite exposure to cyclosporine throughout the pregnancy and having reduced Nephron mass by virtue of their low birth weight we could not find any glomerular or tubular defects, hypertension or prorienuria in 41 children with a mean age of 52 months. We advised against breast feeding in view of the presence of cyclosporine in the mothers’ milk.

Keywords: Post Transplant Pregnancy, Babies’ Outcome and Complications