29 October 2004
Arginase activity concentration marking in monitoring of hepatocytes function after orthtotopic liver transplantation – preliminary reportM Grodzicki, J Pawlak, A Chrzanowka, Z Porembska, M Krawczyk
Ann Transplant 2004; 9(3): 54-57 :: ID: 10219
The constant growth of a liver transplantations performed in Poland is the primary reason for a search for new, better and more exact methods of graft function assessment. They should give an opportunity of early detection of either perfusion disorders or organ’s function deterioration. Thus, the goal of the study was assessment of the usefulness of arginase concentration marking in liver function monitoring after orthotopic transplantation. The group of 5 recipients of orthotopic liver transplants were taken into account. They were performed in 2003, in the Medical University of Warsaw Department of General, Transplant and Liver Surgery. Patients were qualified for the operation according to standards in the center. The indication for the operation was end-stage liver insufficiency. The average age in the study group was 45,6 years. The patient’s serum was taken two hours before the operation. Subsequently, the concentration of arginase activity was marked in serum and bile, first during day 0, 18 hours after the operation, and later at regular intervals during following days until the patient left the clinic, on average from 12 to 14 days. The arithmetical mean values of serum and bile arginase activity values were compared with the average value of a particular parameter, marked during the days following the liver transplant. Serum and bile arginase level fluctuations were assessed in relation to AST, ALT, bilirubin, LDH, alkaline phosphatase (ALKP) and gamma gluthamylo transpeptydase GGTP.
Keywords: Arginase, Liver Transplant, Liver Function Assessment
06 May 2022 : Original articlePhosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of D...
Ann Transplant In Press; DOI: 10.12659/AOT.936293
Most Viewed Current Articles
29 Dec 2021 : Original articleEfficacy and Safety of Tacrolimus-Based Maintenance Regimens in De Novo Kidney Transplant Recipients: A Sys...
Ann Transplant 2021; 26:e933588
26 Jan 2022 : Review articleRecurrence of Hepatocellular Carcinoma After Liver Transplantation: Risk Factors and Predictive Models
Ann Transplant 2022; 27:e934924
24 Jul 2020 : Review articleKidney Transplantation in the Times of COVID-19 – A Literature Review
Ann Transplant 2020; 25:e925755