12 March 2021: Review Paper
Effect of Calcineurin Inhibitors and Mammalian Target of Rapamycin Inhibitors on the Course of COVID-19 in Kidney Transplant Recipients
Nuri Baris Hasbal 1AEF* , Didem Turgut 2AEF , Ebru Gok Oguz 3AEF , Sena Ulu 4AEF , Ozkan Gungor 5AEFDOI: 10.12659/AOT.929279
Ann Transplant 2021; 26:e929279
Background
Pharmacological Action of CNIs and mTORi Related to COVID-19
Effects of CNI and mTORi on Viral Infections
The Mechanism of mTORi-Induced Suppression of Cytokines
Antibody-Dependent Enhancement and Cytokine Storm
Surmising Risks and Benefits of CNI and mTORi for Kidney Transplant Recipients
Effects of CNI and mTORi on Transplantation-Related Oxidative Stress
Conclusions
References
Figure 1 Factors affecting the disease course in kidney recipients.