Sang Youb Han, Jae Il Kim, Eun-Woo Lee, Hye-Yeon Jang, Kum Hyun Han, Se Won Oh, Young-Nam Roh
(Department of Nephrology, Inje University, College of Medicine, Ilsan Paik Hospital, Goyang, South Korea)
Ann Transplant 2017; 22:17-23
This study aimed to explore the factors associated with a family’s delay of decision for organ donation after brain death, and to investigate the effect of such a delay on organ donation.
MATERIAL AND METHODS: Medical records and data on counseling about organ donation with the families of 107 brain-dead potential donors between September 2012 and March 2016 at a single tertiary medical center were retrospectively reviewed.
RESULTS: The final consent rate was 58% (62/107), and successful donation was performed in 40% (43/107). Ninety-two families (86%) made a decision within 48 hours, whereas 15 (14%) required more than 48 hours for a final decision. In univariate and multivariate analyses, the independent factors associated with a decision delay were mean arterial pressure ≤60 mm Hg and coma therapy. In the early decision group (<48 hours), the consent and successful donation rates were 55% (51/92) and 39% (36/92), respectively, whereas in the delayed decision group (≥48 hours), these rates were 73% (11/15) and 47% (7/15), respectively. The consent and successful donation rates were not inferior in the delayed decision group.
CONCLUSIONS: These findings justify continuous efforts to maintain organ viability and to extend counseling to encourage donation even if the family cannot decide immediately.
Keywords: Brain Death, Tissue and Organ Procurement, Tissue Donors