Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

21 May 2009

Liver transplantation in children with biliary atresia and polysplenia syndrome

D Broniszczak, A Apanasiewicz, H Ismail, A Chyżyńska, P Czubkowski, P Kaliciński

Ann Transplant 2009; 14(1): 28-28 :: ID: 880298

Abstract

Background: Children with biliary atresia (BA) and polysplenia syndrome (PS)
have always been considered as a high risk liver transplant recipients due to
technical problems during transplant surgery. We report a single-centre experience with the liver transplantation in children with this syndrome.
Material/Methods: Between 2000 and 2008 330 liver transplants were performed in our centre in children, among them there were five with end stage liver insufficiency, with BA and PS, following the Kasai procedure. They underwent liver transplantation from living (4 patients) and deceased donors
(1 patient). All patients demonstrated additional malformations like: absence  of retrohepatic vena cava (1), intestinal malrotation (2), preduodenal portal vein (1), hepatic artery (2) and cardiac anomalies (2). No situs inversus occurred. Transplantations were performed at the age ranging from 8 months to 11 years. We did not meet serious technical problems during operation, as well as never had to use vascular conduits for graft revascularization.
Results: All patents are alive and well with follow up between 9 and 105 months after transplantation, although one is with persistent hepatitis C and  one has symptoms of portal hypertension after portal thrombosis which occurred during PTLD treatment one year after transplantation.
Conclusions: Results of liver transplantation in children with BA and PS syndrome are as good as for other indications for non-syndromic BA in experienced paediatric liver transplant centre.

Keywords: Liver Transplantation

Add Comment 0 Comments

In Press

08 Mar 2024 : Original article  

Association of Coronary Calcium Score on Cardiac PET During Pre-Kidney Transplant Assessment with Persisten...

Ann Transplant In Press; DOI: 10.12659/AOT.943532  

14 Mar 2024 : Original article  

Impact of Blood Products Transfusion on Patients in the Immediate Post-Lung Transplant Period: A Cohort Study

Ann Transplant In Press; DOI: 10.12659/AOT.943652  

14 Mar 2024 : Case report  

Treatment of Cavernous Transformation of Portal Vein Caused by Hepatic Cystic Echinococcosis Using Ex Vivo ...

Ann Transplant In Press; DOI: 10.12659/AOT.942358  

15 Mar 2024 : Review article  

Approaches and Challenges in the Current Management of Cytomegalovirus in Transplant Recipients: Highlighti...

Ann Transplant In Press; DOI: 10.12659/AOT.941185  

Most Viewed Current Articles

05 Apr 2022 : Original article  

Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver Transplantation

DOI :10.12659/AOT.935604

Ann Transplant 2022; 27:e935604

12 Jan 2022 : Original article  

Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...

DOI :10.12659/AOT.934738

Ann Transplant 2022; 27:e934738

22 Nov 2022 : Original article  

Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...

DOI :10.12659/AOT.937988

Ann Transplant 2022; 27:e937988

15 Mar 2022 : Case report  

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358