21 May 2009
The assessment of residual kidney function after living donor nephrectomy
M Bieniasz, A Kwiatkowski, P Domagała, J Gozdowska, R Kieszek, L Ostrowski, A Deptuła, J Trzebicki, M Durlik, L Pączek, A ChmuraAnn Transplant 2009; 14(1): 25-25 :: ID: 880289
Abstract
Background: The number of patients on the waiting list for kidney transplantation is increasing as a result of cadaveric donor's shortage. One of the ways to expand the donor pool is living donor transplantation. However, only 2-3% of kidney transplants in Poland are obtained from the living related donors. The aim of this study was to assess residual renal function and incidence of microalbuminuria in living kidney donors.
Material/Methods: Between 1995 and 2005, 66 living donor open nephrectomies
were performed. Physical examination, blood and urine tests and ultrasonography were performed prior to nephrectomy and at every follow-up visit (every 12 months post-op) in the donors. Donor mean age was 40.9 years (range 29-60). The donors were predominantly female (52.5%). 27 donors did not report for follow-up visits. Observation period ranged from 36 to 156 months.
Results: Mean creatinine concentration increased from 0.89 mg/dl prior to donation to 1.12 mg/dl and 1.1 mg/dl at 36 and 84 months post nephrectomy, respectively. Mean creatinine clearance according to the Cockroft-Gault formula decreased from 94.27 ml/min prior to donation to 80.2 ml/min and 72.2 ml/min at 36 and 84 months post donation, respectively. Microalbuminuria was observed in one patient (2.6%) at 84 months following nephrectomy.
Conclusions: Living kidney donation results in a reduced creatinine clearance in the donor. Follow-up of living kidney donors is essential in determining risk factors for deterioration of residual kidney function.
Keywords: Kidney Transplantation
In Press
08 Mar 2024 : Original article
Association of Coronary Calcium Score on Cardiac PET During Pre-Kidney Transplant Assessment with Persisten...Ann Transplant In Press; DOI: 10.12659/AOT.943532
14 Mar 2024 : Original article
Impact of Blood Products Transfusion on Patients in the Immediate Post-Lung Transplant Period: A Cohort StudyAnn Transplant In Press; DOI: 10.12659/AOT.943652
14 Mar 2024 : Case report
Treatment of Cavernous Transformation of Portal Vein Caused by Hepatic Cystic Echinococcosis Using Ex Vivo ...Ann Transplant In Press; DOI: 10.12659/AOT.942358
15 Mar 2024 : Review article
Approaches and Challenges in the Current Management of Cytomegalovirus in Transplant Recipients: Highlighti...Ann Transplant In Press; DOI: 10.12659/AOT.941185
Most Viewed Current Articles
05 Apr 2022 : Original article
Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver TransplantationDOI :10.12659/AOT.935604
Ann Transplant 2022; 27:e935604
12 Jan 2022 : Original article
Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...DOI :10.12659/AOT.934738
Ann Transplant 2022; 27:e934738
22 Nov 2022 : Original article
Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...DOI :10.12659/AOT.937988
Ann Transplant 2022; 27:e937988
15 Mar 2022 : Case report
Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...DOI :10.12659/AOT.935860
Ann Transplant 2022; 27:e935860