14 September 2001
Porcine Endogenous Retroviruses(PERVs):Adaptation to Human Cells and Attempts to Infect Small Animals and non-Human Primates
Denner J., Specke V, Schwendemann J, Tacke S. J.Ann Transplant 2001; 6(3): 25-33 :: ID: 497679
Abstract
Zoonoses are diseases that can be transmitted from animals to humans, and there are many examples, including the AIDS pandemic, of this phenomenen. With the advent of xenotransplantation, the definition of zoonoses must be broadened to include "xenozoonoses" or "xenoses", the inadvertent transmissionof pathogens and diseases from animal cells, tissues or organs into human recipients as the result of medical manipulations. Xenotransplantation is defined as the transplantation of live cells, tissues, or organs from one species to another species and includes ex vivo perfusion, the temporary contact outside its own body of blood of one species with cells, tissues or organs of another. Twomain sources of transplants are of clinical relevance for man: transgenic pigs and non-human primates…
Keywords: porcine endogenous retroviruses,, PERVs, Xenotransplantation, Xenozoonoses, animal models
In Press
08 Mar 2024 : Original article
Association of Coronary Calcium Score on Cardiac PET During Pre-Kidney Transplant Assessment with Persisten...Ann Transplant In Press; DOI: 10.12659/AOT.943532
14 Mar 2024 : Original article
Impact of Blood Products Transfusion on Patients in the Immediate Post-Lung Transplant Period: A Cohort StudyAnn Transplant In Press; DOI: 10.12659/AOT.943652
14 Mar 2024 : Case report
Treatment of Cavernous Transformation of Portal Vein Caused by Hepatic Cystic Echinococcosis Using Ex Vivo ...Ann Transplant In Press; DOI: 10.12659/AOT.942358
15 Mar 2024 : Review article
Approaches and Challenges in the Current Management of Cytomegalovirus in Transplant Recipients: Highlighti...Ann Transplant In Press; DOI: 10.12659/AOT.941185
Most Viewed Current Articles
05 Apr 2022 : Original article
Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver TransplantationDOI :10.12659/AOT.935604
Ann Transplant 2022; 27:e935604
12 Jan 2022 : Original article
Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...DOI :10.12659/AOT.934738
Ann Transplant 2022; 27:e934738
22 Nov 2022 : Original article
Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...DOI :10.12659/AOT.937988
Ann Transplant 2022; 27:e937988
15 Mar 2022 : Case report
Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...DOI :10.12659/AOT.935860
Ann Transplant 2022; 27:e935860