Annals of Transplantation

WELCOME TO Annals of Transplantation

Annals of Transplantation is one of the fast-developing journals open to all scientists and fields of transplant medicine and related research. The journal is published quarterly and provides extensive coverage of the most important advances in transplantation.... read more

Current Volume 19, 2014

Published: 2014-04-23

The impact of hepatitis B on heart transplantation: 19 years of national experience in Korea

Hyo-Sun Shin, Hyun-Jai Cho, Eun-Seok Jeon, Ho Young Hwang, Jae-Joong Kim, Ki-Bong Kim, Byung-Hee Oh, Hae-Young Lee

Ann Transplant 2014;19:182-187

DOI: 10.12659/AOT.889680

Background: Hepatitis B virus (HBV) infection is endemic in Korea. With an increasing number of heart transplantation, problems associated with hepatitis B reactivation are becoming an important issue. We aimed to evaluate the functional significance of HBV infection on outcomes of heart transplantation.
Material and Methods: We reviewed all medical records of overall national heart transplantation recipients and donors who had HBV hepatitis at the time of the transplantation, from March 1994 to May 2013. We investigated the HBV serology status, HBV-DNA level of donors and recipients, liver function test, immunosuppressive agent and antiviral agent prescription, and hepatitis morbidity and mortality.
Results: 1) There were 12 HBsAg (+) recipients and 6 HBsAg (+) donors. Median duration of follow-up was...

Keywords: reactivation, antiviral, Hepatitis B virus, Transplantation, Heart


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