eISSN 2329-0358


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Annals of Transplantation is one of the fast-developing journals open to all scientists and fields of transplant medicine and related research. The journal is published quarterly and provides extensive coverage of the most important advances in transplantation.
Using an electronic on-line submission and peer review tracking system, Annals of Transplantation is committed to rapid review and publication. The average time... read more

Published: 2016-05-24

An Arterial Conduit is Not a Risk Factor for Survival Following Orthotopic Liver Transplantation: An Analysis of 20 Years of Liver Transplantation in Innsbruck

Christian Denecke, Sascha Weiss, Matthias Biebl, Josef Fritz, Tomasz Dziodzio, Felix Aigner, Robert Sucher, Andreas Brandl, Claudia Bösmüller, Johann Pratschke, Robert Öllinger

(Department of General, Visceral and Transplantation Surgery, Charite Universitätsmedizin, Berlin, Germany)

Ann Transplant 2016; 21:321-328

DOI: 10.12659/AOT.896659

BACKGROUND: In adult liver transplantation, arterial conduits have been associated with increased risk for vascular complications and inferior outcome.
MATERIAL AND METHODS: Complication rates and outcomes of adult patients undergoing liver transplantation in our center between 1990 and 2012 were analyzed retrospectively. Characteristics, transplantation-related factors, and survival rates of patients with conduit grafts (n=43) were compared to patients with a standard arterial anastomosis (n=904) by univariate and multivariate analysis.
RESULTS: Patients in the conduit group were younger but had a significantly higher proportion of high-urgency and re-transplantations. While patient survival was comparable between the groups, graft survival was inferior for patients with a conduit (1-year, 5-year, and 10-year survival, control vs. conduit group: 87.3%, 78.8% and 71.5% vs. 72.4%, 63.8%, and 41.8%, respectively, p=0.008). In univariate analysis, an arterial conduit was associated with more arterial and biliary complications. However, an arterial conduit was not an independent risk factor for graft or patient survival in a Cox regression analysis.
CONCLUSIONS: An arterial conduit is associated with more vascular complications, yet a conduit per se does not influence graft survival. The inferior outcome may reflect the complex situation of the sicker liver transplant patients needing a non-standard arterial anastomosis.

Keywords: Anastomosis, Surgical, Liver Transplantation, Patient Outcome Assessment

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Published: 2016-05-19

Portosystemic Shunt Surgery in Patients with Idiopathic Noncirrhotic Portal Hypertension

Servet Karagul, Mehmet Ali Yagci, Ali Tardu, Ismail Ertugrul, Serdar Kirmizi, Fatih Sumer, Burak Isik, Cuneyt Kayaalp, Sezai Yilmaz

Ann Transplant 2016; 21:317-320

DOI: 10.12659/AOT.898253

Published: 2016-05-17

Binding of ATGs to Endothelial Cells In Vivo

Andres Beiras-Fernandez, Astrid Hernandez-Sierra, Uwe Schulz, Manfred Richter, Eckart Thein, Anton Moritz, Isabella Werner

Ann Transplant 2016; 21:311-316

DOI: 10.12659/AOT.896158