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Welcome to the Annals of Transplantation

Annals of Transplantation is one of the fast-developing journals open to all scientists and fields of transplant medicine and related research. The journal is published quarterly and provides extensive coverage of the most important advances in transplantation.
Using an electronic on-line submission and peer review tracking system, Annals of Transplantation is committed to rapid review and publication. The average time... read more


Published: 2015-05-25

Technical Refinement of Hepatic Vein Reconstruction in Living Donor Liver Transplantation Using Left Liver Graft

Mitsuhisa Takatsuki, Akihiko Soyama, Masaaki Hidaka, Ayaka Kinoshita, Zhassulan Baimakhanov, Tota Kugiyama, Tomohiko Adachi, Amane Kitasasto, Tamotsu Kuroki, Susumu Eguchi

(Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan)

Ann Transplant 2015; 20:290-296

DOI: 10.12659/AOT.893136


BACKGROUND: In adult living donor liver transplantation (LDLT), left liver graft is generally safer for the donor. The aim of this study was to demonstrate a technical refinement for achieving sufficient outflow using left liver graft.
MATERIAL AND METHODS: Forty-seven cases using left liver were divided into 2 groups according to the procedures of hepatic vein reconstruction: the side-clamp group (21 cases), and the cross-clamp group (26 cases), to sufficiently enlarge the diameter of the hepatic vein with excising the inferior vena cava (IVC).
RESULTS: The liver function tests at 7 days after LDLT were not significantly different between the 2 groups, but the median amount of ascites was significantly greater in the side-clamp group (1250 ml; range, 484–3690) than in the cross-clamp group (582 ml; 190–2785). When we selected the patients with the ratio of graft weight to recipient standard liver volume less than 30%, the 1-year patient survival after transplantation was significantly better in the cross-clamp group than in the side-clamp group (90% in cross-clamp group vs. 71% in side-clamp group, P<0.05).
CONCLUSIONS: In conclusion, hepatic vein reconstruction with cross-clamping of the IVC can secure a sufficient outflow in LDLT using left liver graft.

Keywords: Hepatic Veins, Liver Transplantation, Living Donors




Published: 2015-05-21

Antithymocyte Globulin Dosing Effects on Biopsy-Proven Acute Rejection and Infection Risk


Justin W. Tenney, Samir Mokaddem, Vipul Shah, Ayoola Adekile

Ann Transplant 2015; 20:285-289

DOI: 10.12659/AOT.892966

Published: 2015-05-18

Immunological Factors and Liver Fibrosis in Pediatric Liver Transplant Recipients


Małgorzata Markiewicz-Kijewska, Piotr Kaliciński, Przemysław Kluge, Barbara Piątosa, Irena Jankowska, Aneta Rękawek, Ewa Kostecka, Przemysław N. Kurowski

Ann Transplant 2015; 20:279-284

DOI: 10.12659/AOT.892544