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Using an electronic on-line submission and peer review tracking system, Annals of Transplantation is committed to rapid review and publication. The average time... read more
Using an electronic on-line submission and peer review tracking system, Annals of Transplantation is committed to rapid review and publication. The average time to first decision is around 3-4 weeks. Time to publication of accepted manuscripts continues to be shortened, with the Editorial team committed to a goal of 3 months from acceptance to publication.
Expert reseachers and clinicians from around the world contribute original Articles, Review Papers, Case Reports and Special Reports in every pertinent specialty, providing a lot of arguments for discussion of exciting developments and controversies in the field.
Donor Kidneys with Miliary Papillary Renal Cell Neoplasia: The Role of The Pathologist in Determining Suitability for Transplantation
Albino Eccher, Luigino Boschiero, Francesca Fior, Marilena Casartelli Liviero, Laura Zampicini, Claudio Ghimenton, Antonietta D’Errico-Grigioni, Anna Caliò, Guido Martignoni, Brett Delahunt, Matteo Brunelli
(DAI Pathology and Diagnostics, Azienda Ospedaliera Universitaria Integrata (AOUI) University Hospital, Verona, Italy)
Ann Transplant 2014; 19:362-366
Kidneys with single or multiple tumors, provided that they have histological features recognized as being associated with low risk of recurrence, are considered suitable for transplantation. It is known that kidneys with multiple primary renal tumors show poor renal function and that function dramatically declines when tumors have a miliary configuration. Despite this, no guidelines are in place to differentiate between multifocal tumors and those that are miliary in nature.
Case Report: We report a case in which initial examination revealed papillary renal cell neoplasia in deceased donor kidneys, which were later confirmed on histological and genetic testing to be multiple and miliary in distribution. Gross examination showed closely opposed neoplasms, and on histological examination these were found to...
Keywords: Carcinoma, Renal Cell, multifocal renal cell carcinoma, Tissue Donors, Kidney Transplantation