WELCOME TO Annals of Transplantation
Using an electronic on-line submission and peer review tracking system, Annals of Transplantation is committed to rapid review and publication. The average time to first decision is around 3-4 weeks. Time to publication of accepted manuscripts continues to be shortened, with the Editorial team committed to a goal of 3 months from acceptance to publication.
Expert reseachers and clinicians from around the world contribute original Articles, Review Papers, Case Reports and Special Reports in every pertinent specialty, providing a lot of arguments for discussion of exciting developments and controversies in the field.
Current Volume 19, 2014
Determining eligibility for and preparation to kidney transplantation of a patient with Lynch syndrome – a case report and literature review
Jolanta Gozdowska, Monika Bieniasz, Michał Wszoła, Rafał Kieszek, Piotr Domagała, Jakub Drozdowski, Aleksandra Tomaszek, Artur Kwiatkowski, Andrzej Chmura, Magdalena Durlik
Ann Transplant 2014;19:124-128
Background: Lynch syndrome (HNPCC, hereditary non-polyposis colorectal cancer) is a syndrome of predisposition to cancer inherited in an autosomal dominant fashion. A person with Lynch syndrome has a considerably increased risk of colorectal cancer in comparison with the general population.
Case Report: We present a case of a 24-year-old man with Lynch syndrome (carrying an MLH1 gene mutation) who had colorectal adenocarcinoma diagnosed at 16 years of age. During this time, he had a colectomy performed and chemotherapy was administered (5-FU, CDDP, Leucovorin). Due to hepatic metastases, a decision was made to change chemotherapy to IF with ADM, as a result of which complete remission was obtained. However, kidney failure developed. Its cause was not fully elucidated. The patient was...
Keywords: Kidney Transplantation, Lynch syndrome, malignancies